Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.68 |
| ▸ | CTSK | P43235 | 1/20 | 0.68 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.67 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.67 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.67 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.67 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.67 |
| ▸ | ANPEP | P15144 | 1/20 | 0.66 |
| ▸ | PAM | P19021 | 1/20 | 0.60 |
| ▸ | GNPAT | O15228 | 1/20 | 0.59 |
| ▸ | MMP8 | P22894 | 2/20 | 0.58 |
| ▸ | MMP1 | P03956 | 2/20 | 0.58 |
| ▸ | MMP2 | P08253 | 1/20 | 0.58 |
| ▸ | MMP3 | P08254 | 1/20 | 0.58 |
| ▸ | MMP9 | P14780 | 1/20 | 0.56 |
| ▸ | MMP14 | P50281 | 1/20 | 0.56 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.55 |
| ▸ | TACR1 | P25103 | 1/20 | 0.55 |
| ▸ | FCER2 | P06734 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13956933 | 0.87 | CTSS (0.68) | CTSSCTSKPAMGNPATMMP8 | |
| SCHEMBL23376600 | 0.87 | CTSS (0.68) | CTSSCTSKPAMGNPATMMP8 | |
| SCHEMBL1081111 | 0.85 | GNPAT (0.73) | CTSSCTSKPAMGNPAT | |
| SCHEMBL6677690 | 0.85 | GNPAT (0.73) | CTSSCTSKPAMGNPAT | |
| SCHEMBL6862498 | 0.85 | GRIA1 (0.57) | CTSSCTSKHDAC3HDAC4HDAC1 | |
| SCHEMBL5692056 | 0.85 | GNPAT (0.73) | CTSSCTSKPAMGNPAT | |
| SCHEMBL28747211 | 0.85 | ACACB (0.55) | CTSSCTSKHDAC3HDAC4HDAC1 | |
| SCHEMBL27817100 | 0.85 | GNPAT (0.73) | CTSSCTSKPAMGNPAT | |
| Afalanine SCHEMBL8587729 | 0.84 | CTSS (0.65) | CTSSCTSKPAMGNPATCTRB1 | |
| Afalanine SCHEMBL331330 | 0.84 | CTSS (0.65) | CTSSCTSKPAMGNPATCTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4391747-B2 | — | — | 2009-12-24 | — | — | JP | claimed |
| JP-2004532837-A | — | — | 2004-10-28 | — | — | JP | claimed |
| US-20040176424-A1 | Insecticide and method of controlling insects | NUFARM AUSTRALIA LIMITED (AU) | 2004-09-09 | — | — | US | claimed |
| EP-1385379-A4 | INSECTICIDE AND METHOD OF CONTROLLING INSECTS | NUFARM AUSTRALIA LTD (AU) | 2004-06-23 | — | — | EP | claimed |
| EP-1385379-A1 | INSECTICIDE AND METHOD OF CONTROLLING INSECTS | NUFARM AUSTRALIA LIMITED (AU) | 2004-02-04 | — | — | EP | claimed |
| WO-2002078448-A1 | INSECTICIDE AND METHOD OF CONTROLLING INSECTS | NUFARM AUSTRALIA LIMITED (AU) | 2002-10-10 | — | — | WO | claimed |
| CN-1653040-A | HIF hydroxylase inhibitors | ISIS INNOVATION (GB) | 2005-08-10 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176424-A1 | Insecticide and method of controlling insects | DDT, CYP2B6, NR4A1 | CTSS 3097/4885CTSK 4134/4885HDAC3 18/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.