SCHEMBL443670

SCHEMBL443670

C=C(C(N)=O)C(C)N(CC)CC

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.40
ADRA2A P08913 1/20 0.40
ADRA2B P18089 1/20 0.40
HTR2A P28223 1/20 0.40
HRH1 P35367 1/20 0.40
KCNH2 Q12809 1/20 0.40
TDP1 Q9NUW8 1/20 0.35
BCHE P06276 1/20 0.33
CYP2D6 P10635 1/20 0.33
TSHR P16473 1/20 0.33
CYP2C19 P33261 1/20 0.33
ACHE P22303 1/20 0.33
FDPS P14324 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethyl Chloride SCHEMBL3870935 0.94 PGR (0.37) PGRADRA2AADRA2BHTR2AHRH1
SCHEMBL5965042 0.83 FDPS (0.36) TDP1FDPS
SCHEMBL127513 0.82 PGR (0.47) PGRADRA2AADRA2BHTR2AHRH1
SCHEMBL2828450 0.80 MMP1 (0.36) TDP1TSHR
Chloromethane SCHEMBL4598656 0.78 PGR (0.44) PGRADRA2AADRA2BHTR2AHRH1
SCHEMBL1275887 0.78 MEN1 (0.32) TDP1
Ethyl Chloride SCHEMBL3884054 0.77 PGR (0.43) PGRADRA2AADRA2BHTR2AHRH1
SCHEMBL888048 0.77 TDP1 (0.33) TDP1FDPS
SCHEMBL1432484 0.77 PGR (0.45) PGRADRA2AADRA2BHTR2AHRH1
SCHEMBL27722580 0.77 PGR (0.45) PGRADRA2AADRA2BHTR2AHRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 596 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3660061-B1 RADIOPAQUE MONOMERS, POLYMERS, MICROSPHERES, AND METHODS RELATED THERETO BIOSPHERE MEDICAL INC (US) 2023-06-21 EP claimed
EP-3245236-B1 RADIOPAQUE MONOMERS, POLYMERS, MICROSPHERES, AND METHODS RELATED THERETO BIOSPHERE MEDICAL INC (US) 2020-09-23 EP claimed
EP-2351779-B1 Microspheres and method of making the microspheres BIOSPHERE MEDICAL INC (US) 2019-04-24 EP claimed
US-10166527-B2 Surface modification of porous base supports MERCK PATENT GMBH (DE) 2019-01-01 US claimed
US-10022469-B2 Microspheres useful for therapeutic vascular embolization BioSphere Medical, SA (US) 2018-07-17 US claimed
EP-2310104-B1 MIXED GRAFT POLYMERS FOR ION EXCHANGE CHROMATOGRAPHY MERCK PATENT GMBH (DE) 2017-10-18 EP claimed
US-20160361458-A1 MICROSPHERES USEFUL FOR THERAPEUTIC VASCULAR EMBOLIZATION BIOSPHERE MEDICAL SA (FR) 2016-12-15 US claimed
US-9439861-B2 Microspheres useful for therapeutic vascular embolization BioSphere Medical, SA (US) 2016-09-13 US claimed
US-9295648-B2 Injectable microspheres for dermal augmentation and tissue bulking BIOSPHERE MEDICAL, INC. (US) 2016-03-29 US claimed
US-20150298097-A1 SURFACE MODIFICATION OF POROUS BASE SUPPORTS MERCK PATENT GMBH (DE) 2015-10-22 US claimed
US-5075371-A COMPOSITE POLYMERS AND THEIR PREPARATION WHICH ARE USEFUL IN LIQUID CHROMATOGRAPHY I.B.F. (FR) 1991-12-24 US claimed
US-5053135-A COMPOSITE POLYMERS, THEIR PREPARATION AND THEIR USE IN LIQUID CHROMATOGRAPHY I.B.F. (FR) 1991-10-01 US claimed
US-5021167-A Oil in water emulsion NALCO CHEMICAL COMPANY (US) 1991-06-04 US claimed
EP-0373626-A2 Cell culture carriers MITSUBISHI KASEI CORPORATION (JP) 1990-06-20 EP claimed
US-4931191-A Method for separating solids from water using amine containing polymers NALCO CHEMICAL COMPANY (US) 1990-06-05 US claimed
EP-0331528-A1 Antimicrobial ethylene copolymers and compositions thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-09-06 EP claimed
US-4842987-A Photosensitive element for producing printing plates or resist images BASF AKTIENGESELLSCHAFT (DE) 1989-06-27 US claimed
US-4699951-A MIXTURE OF VINYL HOMOPOLYMER AND, ACRYLAMIDE COPOLYMERIZED WITH VINYL POLYMER NALCO CHEMICAL COMPANY (US) 1987-10-13 US claimed
US-4020192-A AMINO ALKYL AMIDE ACRYLIC POLYMER FUJI XEROX CO., LTD. (JA) 1977-04-26 US claimed
US-4013513-A Ion exchange chromatographic isoenzyme separation and isolation E-C APPARATUS CORPORATION (US) 1977-03-22 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10022469-B2 Microspheres useful for therapeutic vascular embolization CD68, FGB, MB PGR 2202/4885ADRA2A 2473/4885ADRA2B 2303/4885
US-20160361458-A1 MICROSPHERES USEFUL FOR THERAPEUTIC VASCULAR EMBOLIZATION CD68, FGB, MB PGR 2202/4885ADRA2A 2473/4885ADRA2B 2303/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.