SCHEMBL4436790

SCHEMBL4436790

C=CC/[C]=C/c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.44
TSHR P16473 2/20 0.44
MAOB P27338 1/20 0.39
TRPA1 O75762 3/20 0.33
LMNA P02545 2/20 0.33
MAPK1 P28482 2/20 0.33
ALOX5 P09917 1/20 0.33
CYP2A6 P11509 1/20 0.33
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
NFE2L2 Q16236 2/20 0.31
MMP1 P03956 1/20 0.31
MMP9 P14780 1/20 0.31
MMP12 P39900 1/20 0.31
MAPT P10636 2/20 0.31
CYP2C19 P33261 2/20 0.31
MITF O75030 1/20 0.30
PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8892651 0.71 MAOB (0.42) ALDH1A1TSHRMAOBTRPA1LMNA
SCHEMBL2311225 0.71 MAOB (0.42) ALDH1A1TSHRMAOBTRPA1LMNA
SCHEMBL8863221 0.71 MAOB (0.42) ALDH1A1TSHRMAOBTRPA1LMNA
SCHEMBL3808266 0.71 MAOB (0.42) ALDH1A1TSHRMAOBTRPA1LMNA
SCHEMBL5083636 0.71 MAOB (0.42) ALDH1A1TSHRMAOBTRPA1LMNA
SCHEMBL1509680 0.71 MAOB (0.42) ALDH1A1TSHRMAOBTRPA1LMNA
SCHEMBL9853133 0.70 MAOB (0.40) ALDH1A1TSHRMAOBTRPA1LMNA
SCHEMBL1195145 0.70 MAOB (0.40) ALDH1A1TSHRMAOBTRPA1LMNA
Styrene SCHEMBL28107406 0.70 ALDH1A1 (0.58) ALDH1A1TSHRMAOBMEN1KMT2A
SCHEMBL3907718 0.69 ALDH1A1 (0.50) ALDH1A1TSHRMAOBTRPA1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090178760-A1 METHOD FOR BONDING GLASS MEMBER FOR OPTICAL COMMUNICATION OMRON CORPORATION 2009-07-16 US claimed
US-6034185-A HARDENER IS A POLYALKYL PHENOLIC RESIN CHANG CHUN PLASTICS CO., LTD. (TW) 2000-03-07 US claimed
US-5552551-A COLORS FOR PHOSPHORESCENCE FLORIDA STATE UNIVERSITY (US) 1996-09-03 US claimed
WO-1995003343-A1 PROTON-TRANSFER, LOW SELF-ABSORBING CHROMOPHORES FOR USE IN SCINTILLATORS FLORIDA STATE UNIVERSITY (US) 1995-02-02 WO claimed
US-4883844-A FROM AROMATIC ALDEHYDE AND SUBSTITUTED PYRIDINE THE DOW CHEMICAL COMPANY (US) 1989-11-28 US claimed
US-20190245150-A1 AROMATIC COMPOUND AND USE THEREOF RIKEN (JP) 2019-08-08 US disclosed
EP-3486247-A1 AROMATIC COMPOUND AND USE THEREOF Riken (JP) 2019-05-22 EP disclosed
US-6034185-A HARDENER IS A POLYALKYL PHENOLIC RESIN CHANG CHUN PLASTICS CO., LTD. (TW) 2000-03-07 US disclosed
US-6034185-A HARDENER IS A POLYALKYL PHENOLIC RESIN CHANG CHUN PLASTICS CO., LTD. (TW) 2000-03-07 US disclosed
US-5552551-A COLORS FOR PHOSPHORESCENCE FLORIDA STATE UNIVERSITY (US) 1996-09-03 US disclosed
US-5552551-A COLORS FOR PHOSPHORESCENCE FLORIDA STATE UNIVERSITY (US) 1996-09-03 US disclosed
WO-1995003343-A1 PROTON-TRANSFER, LOW SELF-ABSORBING CHROMOPHORES FOR USE IN SCINTILLATORS FLORIDA STATE UNIVERSITY (US) 1995-02-02 WO disclosed
WO-1995003343-A1 PROTON-TRANSFER, LOW SELF-ABSORBING CHROMOPHORES FOR USE IN SCINTILLATORS FLORIDA STATE UNIVERSITY (US) 1995-02-02 WO disclosed
US-4945138-A Styrylaza vinyl esters THE DOW CHEMICAL COMPANY (US) 1990-07-31 US disclosed
US-4883844-A FROM AROMATIC ALDEHYDE AND SUBSTITUTED PYRIDINE THE DOW CHEMICAL COMPANY (US) 1989-11-28 US disclosed
US-4851483-A FROM EPOXIDIZED HYDROXYSTYRYLAZA COMPOUNDS DERIVED FROM AROMATIC HYDROXYALDEHYDES AND METHYLATED PYRIDINES OR PYRAZINES THE DOW CHEMICAL COMPANY (US) 1989-07-25 US disclosed
EP-0320836-A2 Halogen-free flame-resistant moulding compositions, process for their preparation une their use BASF Aktiengesellschaft (DE) 1989-06-21 EP disclosed
US-4540745-A Allyl styryl pyridines and pyrazines and polymers thereof THE DOW CHEMICAL COMPANY (US) 1985-09-10 US disclosed
US-4540745-A Allyl styryl pyridines and pyrazines and polymers thereof THE DOW CHEMICAL COMPANY (US) 1985-09-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190245150-A1 AROMATIC COMPOUND AND USE THEREOF SLC43A1, SLCO2A1, SLCO4C1 ALDH1A1 967/4885TSHR 2628/4885MAOB 329/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.