Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31483488 | 0.75 | TSHR (0.38) | HSD17B10GAAGFERALDH1A1TSHR | |
| SCHEMBL7693285 | 0.73 | APP (0.43) | APPHSD17B10GAAS1PR2S1PR1 | |
| SCHEMBL28387485 | 0.71 | APP (0.38) | APPS1PR2S1PR1S1PR3PDE10A | |
| SCHEMBL2423001 | 0.71 | NOS3 (0.44) | HSD17B10GAAGFERALDH1A1TSHR | |
| SCHEMBL4940219 | 0.71 | CD44 (0.37) | APPS1PR2S1PR1S1PR3ALDH1A1 | |
| SCHEMBL10880887 | 0.71 | MGLL (0.43) | GAAS1PR2S1PR1S1PR3ALDH1A1 | |
| SCHEMBL6812392 | 0.70 | S1PR1 (0.42) | APPHSD17B10S1PR2S1PR1S1PR3 | |
| SCHEMBL1257433 | 0.70 | ALDH1A1 (0.36) | APPS1PR2S1PR1S1PR3ALDH1A1 | |
| SCHEMBL7250141 | 0.70 | SLC2A1 (0.49) | HSD17B10GAAALDH1A1TSHR | |
| SCHEMBL11583150 | 0.69 | HTT (0.39) | HSD17B10GAAGFERALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2021415-A2 | DYE COMPOUNDS AND THE USE OF THEIR LABELLED CONJUGATES | Solexa Limited (GB) | 2009-02-11 | — | — | EP | disclosed |
| WO-2007135368-A2 | DYE COMPOUNDS AND THE USE OF THEIR LABELLED CONJUGATES | SOLEXA LIMITED (GB) | 2007-11-29 | — | — | WO | disclosed |