Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | RECQL | P46063 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6812392 | 0.91 | S1PR1 (0.42) | APPCYP2D6ALDH1A1RAB9AKDM4E | |
| SCHEMBL27484653 | 0.77 | S1PR1 (0.38) | APPALDH1A1HSD17B10S1PR2S1PR1 | |
| SCHEMBL6742162 | 0.77 | ALDH1A1 (0.41) | LMNABLMALDH1A1TSHRKDM4E | |
| SCHEMBL4940219 | 0.77 | CD44 (0.37) | APPCYP2D6ALDH1A1TSHRKDM4E | |
| SCHEMBL1257433 | 0.76 | ALDH1A1 (0.36) | APPCYP2D6ALDH1A1TSHRKDM4E | |
| SCHEMBL27678030 | 0.75 | TTR (0.41) | APPCYP2D6LMNABLMSLC6A6 | |
| SCHEMBL11285123 | 0.75 | MGLL (0.40) | APPCYP2D6LMNABLMSLC6A6 | |
| Sulfuric Acid SCHEMBL3983159 | 0.74 | CA2 (0.41) | LMNABLMALDH1A1RAB9ARECQL | |
| SCHEMBL4437046 | 0.73 | APP (0.34) | APPCYP2D6ALDH1A1TSHRHSD17B10 | |
| SCHEMBL28387485 | 0.73 | APP (0.38) | APPCYP2D6LMNABLMSLC6A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6340596-B1 | COLORIMETRIC ANALYSIS; REACTING HYDROGEN SULFIDE WITH P-(DIALKYLAMINO)-ANILINE DERIVATIVE AND OXIDIZING AGENT UNDER ACIDIC CONDITIONS | FUJIREBIO INC. (JP) | 2002-01-22 | — | — | US | claimed |
| US-6340596-B1 | COLORIMETRIC ANALYSIS; REACTING HYDROGEN SULFIDE WITH P-(DIALKYLAMINO)-ANILINE DERIVATIVE AND OXIDIZING AGENT UNDER ACIDIC CONDITIONS | FUJIREBIO INC. (JP) | 2002-01-22 | — | — | US | disclosed |
| EP-0936466-A2 | Reagent composition for measuring hydrogen sulfide and method for measuring hydrogen sulfide | FUJIREBIO INC. (JP) | 1999-08-18 | — | — | EP | disclosed |