Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 14/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11638601 | 0.85 | CYP2B6 (0.50) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL6552278 | 0.81 | CYP2B6 (0.62) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL11541847 | 0.76 | SMN1; SMN2 (0.54) | CYP3A4MEN1KMT2ASMN1; SMN2CYP2B6 | |
| SCHEMBL5139721 | 0.76 | OPRD1 (0.49) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL16079079 | 0.71 | DRD2 (0.51) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL7834385 | 0.69 | L3MBTL1 (0.42) | CHRM3CHRM2CYP2B6LMNA | |
| SCHEMBL10587965 | 0.68 | CARM1 (0.50) | CHRM3CHRM2CHRM1CYP3A4KCNH2 | |
| SCHEMBL10438560 | 0.67 | DRD2 (0.56) | CYP3A4MEN1POLBKMT2ASMN1; SMN2 | |
| SCHEMBL16076524 | 0.66 | CHRNB4 (0.39) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| Dimethylphenylpiperazinium SCHEMBL3453554 | 0.65 | CHRNA7 (1.00) | CHRNA4CYP3A4ALOX15CHRNB2NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2026807-A1 | USE OF PARASYMPATHOLYTIC SUBSTANCES TO ENHANCE AND ACCELERATE STEM CELL DIFFERENTIATION, RELATED METHOD AND COMPOSITIONS | Universita' Degli Studi di Torino (IT) | 2009-02-25 | — | — | EP | disclosed |
| WO-2007135574-A1 | USE OF PARASYMPATHOLYTIC SUBSTANCES TO ENHANCE AND ACCELERATE STEM CELL DIFFERENTIATION, RELATED METHOD AND COMPOSITIONS | UNIVERSITA' DEGLI STUDI DI TORINO (IT) | 2007-11-29 | — | — | WO | disclosed |