Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TYMS | P04818 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2351664 | 1.00 | DPP4 (0.39) | DPP4ALDH1A1TYMSTSHRKDM4E | |
| SCHEMBL2346142 | 0.90 | ALDH1A1 (0.43) | DPP4ALDH1A1TYMSTSHRKDM4E | |
| SCHEMBL2587508 | 0.90 | FFAR2 (0.38) | DPP4ALDH1A1TYMSTSHRKDM4E | |
| SCHEMBL3589461 | 0.85 | TYMS (0.41) | ALDH1A1TYMSGPR119TDP1MEN1 | |
| SCHEMBL2351853 | 0.85 | TYMS (0.41) | ALDH1A1TYMSGPR119TDP1MEN1 | |
| SCHEMBL4441921 | 0.85 | TYMS (0.41) | ALDH1A1TYMSGPR119TDP1MEN1 | |
| SCHEMBL20835401 | 0.85 | TYMS (0.35) | DPP4ALDH1A1TYMSTSHRKDM4E | |
| SCHEMBL2587662 | 0.84 | DPP4 (0.41) | DPP4ALDH1A1TYMSTSHRKDM4E | |
| SCHEMBL20835437 | 0.84 | L3MBTL1 (0.41) | DPP4ALDH1A1TYMSTSHRKDM4E | |
| SCHEMBL2584143 | 0.84 | RIPK1 (0.46) | ALDH1A1TYMSGPR119TDP1RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125829-A2 | BICYCLIC OXOMORPHOLINE DERIVATIVE | Eisai R&D Management Co., Ltd. (JP) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008108378-A2 | BICYCLIC OXOMORPHOLINE DERIVATIVE | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2008-09-12 | — | — | WO | disclosed |