SCHEMBL4437767

SCHEMBL4437767

C(=C/C1C2CC3CC(C2)CC1(/C=C/c1ccccc1)C3)\c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 2/20 0.40
GABBR2 O75899 1/20 0.36
GABRB1 P18505 1/20 0.36
GABRB2 P47870 1/20 0.36
GABBR1 Q9UBS5 1/20 0.36
SIGMAR1 Q99720 3/20 0.34
GRIN2D O15399 2/20 0.34
GRIN3B O60391 2/20 0.34
GRIN1 Q05586 2/20 0.34
GRIN2A Q12879 2/20 0.34
GRIN2B Q13224 2/20 0.34
GRIN2C Q14957 2/20 0.34
GRIN3A Q8TCU5 2/20 0.34
CHRNA7 P36544 1/20 0.34
HPGD P15428 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
LMNA P02545 2/20 0.32
GAA P10253 1/20 0.32
MEN1 O00255 1/20 0.31
JAK2 O60674 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4437770 1.00 KDM1A (0.40) KDM1AGABBR2GABRB1GABRB2GABBR1
SCHEMBL3850618 0.83 GABBR2 (0.38) KDM1AGABBR2GABRB1GABRB2GABBR1
SCHEMBL3850620 0.83 GABBR2 (0.38) KDM1AGABBR2GABRB1GABRB2GABBR1
SCHEMBL28480393 0.73 CHRNA7 (0.43) KDM1AGABBR2GABRB1GABRB2GABBR1
SCHEMBL28274136 0.73 CHRNA7 (0.43) KDM1AGABBR2GABRB1GABRB2GABBR1
SCHEMBL3849799 0.72 GRIN2D (0.33) GABBR2GABRB1GABRB2GABBR1SIGMAR1
SCHEMBL1397163 0.64 CHRNA7 (0.42) KDM1AGABBR2GABRB1GABRB2GABBR1
SCHEMBL3849792 0.64 GABBR2 (0.36) KDM1AGABBR2GABRB1GABRB2GABBR1
SCHEMBL3849794 0.64 GABBR2 (0.36) KDM1AGABBR2GABRB1GABRB2GABBR1
SCHEMBL3840995 0.64 GRIN2D (0.39) KDM1AGABBR2GABRB1GABRB2GABBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7612155-B2 Film forming composition, insulating film formed by use of the composition, and electronic device FUJIFILM CORPORATION (JP) 2009-11-03 US disclosed
US-20070255003-A1 Film forming composition, insulating film formed by use of the composition, and electronic device FUJIFILM CORPORATION (JP) 2007-11-01 US disclosed
US-20030143332-A1 Coating solution for forming insulating film SUMITOMO CHEMICAL COMPANY, LIMITED 2003-07-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070255003-A1 Film forming composition, insulating film formed by use of the composition, and electronic device C1S, C1R, MLX KDM1A 900/4885GABBR2 3889/4885GABRB1 3614/4885
US-20030143332-A1 Coating solution for forming insulating film TET1, TAS1R1, ITGA1 KDM1A 19/4885GABBR2 1105/4885GABRB1 1174/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.