Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15397518 | 0.84 | GPBAR1 (0.42) | MEN1KMT2ACES2L3MBTL1 | |
| SCHEMBL7993902 | 0.82 | OPRM1 (0.46) | MEN1KMT2ACES2HDAC1HDAC6 | |
| SCHEMBL4632782 | 0.81 | MEN1 (0.44) | MEN1KMT2ALTB4R2HDAC1HDAC6 | |
| SCHEMBL20357360 | 0.81 | MEN1 (0.44) | MEN1KMT2ACES2LTB4R2HDAC1 | |
| SCHEMBL10700469 | 0.80 | MEN1 (0.54) | MEN1KMT2ACES2CYP1A2CYP3A4 | |
| SCHEMBL4440953 | 0.80 | LTB4R2 (0.43) | MEN1KMT2ACES2LTB4R2HDAC1 | |
| SCHEMBL1334800 | 0.78 | HDAC1 (0.49) | MEN1KMT2ALTB4R2HDAC1HDAC6 | |
| SCHEMBL7791465 | 0.76 | HDAC3 (0.51) | MEN1KMT2ALTB4R2HDAC1HDAC6 | |
| SCHEMBL1847416 | 0.76 | CES2 (0.50) | MEN1KMT2ACES2SRD5A2MAPT | |
| SCHEMBL1703719 | 0.74 | CES2 (0.49) | MEN1KMT2ACES2SRD5A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121598-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008076754-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-06-26 | — | — | WO | disclosed |