Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 6/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PTPRB | P23467 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PTGIR | P43119 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5809314 | 0.83 | LTB4R2 (0.41) | LTB4R2ACHERAB9APTPRBCES2 | |
| SCHEMBL6827496 | 0.80 | RAB9A (0.53) | LTB4R2ACHERAB9APTPRBALDH1A1 | |
| SCHEMBL7791465 | 0.80 | HDAC3 (0.51) | LTB4R2RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL4437768 | 0.80 | MEN1 (0.54) | LTB4R2RAB9ACES2MEN1KMT2A | |
| SCHEMBL6831433 | 0.79 | LTB4R2 (0.54) | LTB4R2RAB9APTPRBMEN1KMT2A | |
| SCHEMBL4089396 | 0.79 | CHRM2 (0.52) | LTB4R2RAB9APTPRBALDH1A1MEN1 | |
| SCHEMBL9015909 | 0.78 | MAPT (0.46) | ACHERAB9ACES2CES1ALDH1A1 | |
| SCHEMBL38650580 | 0.78 | MAPT (0.46) | ACHERAB9ACES2CES1ALDH1A1 | |
| SCHEMBL4677800 | 0.78 | LTB4R2 (0.50) | LTB4R2RAB9APTPRBALDH1A1MEN1 | |
| SCHEMBL6178653 | 0.78 | LTB4R2 (0.44) | LTB4R2ACHERAB9AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121598-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008076754-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-06-26 | — | — | WO | disclosed |