SCHEMBL4438291

SCHEMBL4438291

C#Cc1cccc(O)c1N.c1cc2cc-2c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.41
ESR1 P03372 3/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
ALOX15 P16050 2/20 0.36
HSD17B10 Q99714 2/20 0.36
KDM4E B2RXH2 1/20 0.36
USP2 O75604 1/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
HSP90AA1 P07900 1/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36
HPGD P15428 1/20 0.36
ALOX12 P18054 1/20 0.36
HTT P42858 1/20 0.36
G6PD P11413 1/20 0.36
CASP7 P55210 1/20 0.36
CASP6 P55212 1/20 0.36
HDAC4 P56524 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11193381 0.89 G6PD (0.38) APPESR1MEN1KMT2AALOX15
SCHEMBL8955706 0.82 APP (0.45) APPESR1MEN1KMT2AALOX15
SCHEMBL688661 0.75 PTPN1 (0.32) MEN1KMT2AHSD17B10KDM4EALDH1A1
SCHEMBL16720070 0.74 AR (0.41) APPESR1MEN1KMT2AKDM4E
SCHEMBL19405722 0.73 G6PD (0.45) APPALOX15HSD17B10KDM4EALDH1A1
SCHEMBL1926846 0.72 ALDH1A1 (0.46) MEN1KMT2AALOX15HSD17B10KDM4E
SCHEMBL1808224 0.71 ALDH1A1 (0.55) MEN1KMT2AALOX15HSD17B10KDM4E
SCHEMBL2183097 0.70 G6PD (0.47) MEN1KMT2AALOX15HSD17B10KDM4E
SCHEMBL944242 0.70 G6PD (0.42) ALOX15HSD17B10KDM4EALDH1A1LMNA
SCHEMBL28988401 0.70 ALDH1A1 (0.48) APPESR1MEN1KMT2AALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7608928-B2 Laminated body and semiconductor device JSR CORPORATION (JP) 2009-10-27 US disclosed
US-20080044664-A1 Laminated Body and Semiconductor Drive JSR CORPORATION (JP) 2008-02-21 US disclosed
EP-1760774-A1 LAMINATED BODY AND SEMICONDUCTOR DEVICE JSR Corporation (JP) 2007-03-07 EP disclosed