SCHEMBL8955706

SCHEMBL8955706

C#Cc1ccccc1O.c1cc2cc-2c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.45
HDAC4 P56524 1/20 0.44
HDAC2 Q92769 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
ESR1 P03372 3/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
ACMSD Q8TDX5 1/20 0.39
ALOX5 P09917 1/20 0.39
BACE1 P56817 1/20 0.38
ALDH1A1 P00352 4/20 0.37
HPGD P15428 3/20 0.37
HSD17B10 Q99714 3/20 0.37
HSD17B1 P14061 3/20 0.37
HSD17B2 P37059 3/20 0.37
CYP3A4 P08684 2/20 0.37
BCL2L1 Q07817 1/20 0.37
CYP2C9 P11712 1/20 0.37
ABL1 P00519 1/20 0.36
ABCB1 P08183 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL596947 0.87
SCHEMBL30267598 0.87
SCHEMBL1180219 0.85 ALDH1A1 (0.41) APPHDAC4HDAC2HDAC8ESR1
SCHEMBL4438291 0.82 APP (0.41) APPHDAC4HDAC2HDAC8ESR1
SCHEMBL16720070 0.79 AR (0.41) APPESR1MEN1KMT2AALDH1A1
SCHEMBL28773472 0.78 ALDH1A1 (0.40) HDAC4HDAC2HDAC8ESR1ALOX5
SCHEMBL948906 0.78 ALOX5 (0.57) APPHDAC4HDAC2HDAC8ESR1
SCHEMBL28504938 0.75 CYP11B1 (0.37) ESR1MEN1KMT2AHSD17B1HSD17B2
SCHEMBL28493060 0.75 TSHR (0.45) APPESR1MEN1KMT2AALDH1A1
SCHEMBL1808224 0.75 ALDH1A1 (0.55) MEN1KMT2AALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150274886-A1 Crosslinkable Soluble Aromatic Polyester TICONA LLC 2015-10-01 US claimed
US-9145519-B2 Crosslinkable aromatic polyester TICONA LLC (US) 2015-09-29 US claimed
WO-2014047015-A1 CROSSLINKABLE AROMATIC POLYESTER TICONA LLC (US) 2014-03-27 WO claimed
US-20140088247-A1 Crosslinkable Aromatic Polyester TICONA LLC (US) 2014-03-27 US claimed
CN-108884242-B Prepreg product and composite product comprising fibres and a liquid crystalline thermoset precursor 阿罗特罗皮卡科技公司 2021-11-26 CN disclosed
US-11001013-B2 Pre-preg and composite products comprising fibers and a liquid crystal thermoset precursor ALLOTROPICA TECHNOLOGIES INC. (US) 2021-05-11 US disclosed
CN-111233610-A Synthesis method of trans-olefin compound 五邑大学 2020-06-05 CN disclosed
EP-3405513-B1 PRE-PREG AND COMPOSITE PRODUCTS COMPRISING FIBERS AND A LIQUID CRYSTAL THERMOSET PRECURSOR ALLOTROPICA TECH INC (US) 2020-03-18 EP disclosed
US-20190039331-A1 PRE-PREG AND COMPOSITE PRODUCTS COMPRISING FIBERS AND A LIQUID CRYSTAL THERMOSET PRECURSOR ALLOTROPICA TECHNOLOGIES INC. 2019-02-07 US disclosed
EP-3405513-A1 PRE-PREG AND COMPOSITE PRODUCTS COMPRISING FIBERS AND A LIQUID CRYSTAL THERMOSET PRECURSOR Allotropica Technologies Inc. (US) 2018-11-28 EP disclosed
US-20170267824-A1 PREPREG COMPOSITE CONTAINING A CROSSLINKED AROMATIC POLYESTER TICONA LLC 2017-09-21 US disclosed
WO-2017125887-A1 PRE-PREG AND COMPOSITE PRODUCTS COMPRISING FIBERS AND A LIQUID CRYSTAL THERMOSET PRECURSOR ALLOTROPICA TECHNOLOGIES INC. (US) 2017-07-27 WO disclosed
US-20150274886-A1 Crosslinkable Soluble Aromatic Polyester TICONA LLC 2015-10-01 US disclosed
US-9145519-B2 Crosslinkable aromatic polyester TICONA LLC (US) 2015-09-29 US disclosed
WO-2014047015-A1 CROSSLINKABLE AROMATIC POLYESTER TICONA LLC (US) 2014-03-27 WO disclosed
US-20140088247-A1 Crosslinkable Aromatic Polyester TICONA LLC (US) 2014-03-27 US disclosed
US-5493002-A Aryl ethynyl phthalic anhydrides and polymers with terminal or pendant amines prepared with aryl ethynyl phthalic anhydrides VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) 1996-02-20 US disclosed