Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.34 |
| ▸ | CTSS | P25774 | 2/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4429647 | 0.91 | CTSS (0.38) | CTSLCTSSCTSB | |
| SCHEMBL4432656 | 0.91 | CTSS (0.40) | CTSLCTSSCTSB | |
| SCHEMBL4429530 | 0.82 | CTSL (0.42) | CTSLCTSSCTSB | |
| SCHEMBL4432030 | 0.82 | CTSL (0.34) | CTSLCTSSCTSB | |
| SCHEMBL4428147 | 0.81 | CTSL (0.40) | CTSLCTSSCTSB | |
| SCHEMBL4429535 | 0.78 | CTSL (0.41) | CTSLCTSSCTSB | |
| SCHEMBL3320272 | 0.78 | GPR119 (0.34) | CTSLCTSS | |
| SCHEMBL3319603 | 0.77 | CTSS (0.34) | CTSS | |
| Trifluoroacetic Acid SCHEMBL3319601 | 0.76 | CTSS (0.34) | CTSS | |
| SCHEMBL3315733 | 0.73 | CTSS (0.43) | CTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2118106-A1 | PURINES AS CYSTEINE PROTEASE INHIBITORS | Glaxo Group Limited (GB) | 2009-11-18 | — | — | EP | claimed |
| WO-2008107368-A1 | PURINES AS CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2008-09-12 | — | — | WO | claimed |
| EP-2118106-A1 | PURINES AS CYSTEINE PROTEASE INHIBITORS | Glaxo Group Limited (GB) | 2009-11-18 | — | — | EP | disclosed |
| WO-2008107368-A1 | PURINES AS CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2008-09-12 | — | — | WO | disclosed |