Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 6/20 | 0.46 |
| ▸ | CA2 | P00918 | 6/20 | 0.46 |
| ▸ | CA9 | Q16790 | 6/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27953436 | 0.82 | LMNA (0.51) | LMNAMEN1KMT2AALDH1A1CA1 | |
| SCHEMBL4524583 | 0.80 | CYP1A2 (0.57) | RXFP1LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL3494987 | 0.78 | LMNA (0.58) | RXFP1LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL2698820 | 0.77 | RXFP1 (0.62) | RXFP1LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL5667998 | 0.76 | FADS1 (0.61) | RXFP1LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL4247807 | 0.75 | ALDH1A1 (0.54) | RXFP1LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL18098214 | 0.75 | RXFP1 (0.64) | RXFP1LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL1592707 | 0.74 | LMNA (0.53) | RXFP1LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL15256305 | 0.74 | ALDH1A1 (0.63) | RXFP1LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL16127847 | 0.74 | ALDH1A1 (0.65) | RXFP1LMNAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2200977-A2 | F1F0-ATPASE INHIBITORS AND RELATED METHODS | The Regents of the University of Michigan (US) | 2010-06-30 | — | — | EP | disclosed |
| WO-2009036175-A2 | F1F0-ATPASE INHIBITORS AND RELATED METHODS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2009-03-19 | — | — | WO | disclosed |