Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4524583 | 0.85 | CYP1A2 (0.57) | ALDH1A1KMT2AMEN1LMNACSNK2A1 | |
| SCHEMBL2177704 | 0.84 | ALDH1A1 (0.58) | ALDH1A1KMT2AMEN1LMNACSNK2A1 | |
| SCHEMBL11753236 | 0.81 | GPR35 (0.65) | ALDH1A1KMT2AMEN1LMNACSNK2A1 | |
| SCHEMBL30266262 | 0.81 | ALDH1A1 (0.58) | ALDH1A1KMT2AMEN1LMNACSNK2A1 | |
| SCHEMBL15461385 | 0.81 | ALDH1A1 (0.58) | ALDH1A1KMT2AMEN1LMNACSNK2A1 | |
| SCHEMBL3494987 | 0.79 | LMNA (0.58) | ALDH1A1KMT2AMEN1LMNACSNK2A1 | |
| SCHEMBL27817425 | 0.79 | MEN1 (0.68) | ALDH1A1KMT2AMEN1LMNACSNK2A1 | |
| SCHEMBL4439620 | 0.78 | CA1 (0.77) | ALDH1A1KMT2AMEN1LMNAMAPT | |
| SCHEMBL1592707 | 0.78 | LMNA (0.53) | ALDH1A1KMT2AMEN1LMNACSNK2A1 | |
| SCHEMBL12049667 | 0.78 | KMT2A (0.56) | ALDH1A1KMT2AMEN1LMNACSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090163518-A1 | Novel Compounds | ASTRAZENECA AB (SE) | 2009-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163518-A1 | Novel Compounds | IDO1, IDO2, MTNR1A | ALDH1A1 768/4885KMT2A 3674/4885MEN1 3577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.