Diphenylamine

Diphenylamine

SCHEMBL4439637

CCC(C)N(C)c1ccc(N(C)C(C)CC)cc1.c1ccc(Nc2ccccc2)cc1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.46
KMT2A Q03164 5/20 0.46
ALDH1A1 P00352 8/20 0.44
HSD17B10 Q99714 4/20 0.44
ALOX15 P16050 3/20 0.44
TSHR P16473 3/20 0.44
ALOX12 P18054 3/20 0.44
L3MBTL1 Q9Y468 3/20 0.44
TDP1 Q9NUW8 3/20 0.44
CYP3A4 P08684 2/20 0.44
LMNA P02545 2/20 0.44
THRB P10828 1/20 0.44
RECQL P46063 1/20 0.44
ATM Q13315 1/20 0.44
MAPK1 P28482 3/20 0.42
HIF1A Q16665 1/20 0.42
PTGS1 P23219 1/20 0.41
SLC6A2 P23975 1/20 0.41
PTGS2 P35354 1/20 0.41
HTR2B P41595 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11728189 0.98 MEN1 (0.49) MEN1KMT2AALDH1A1HSD17B10ALOX15
SCHEMBL95074 0.85 TSHR (0.42) MEN1KMT2AALDH1A1TSHRLMNA
SCHEMBL39602 0.82 ALDH1A1 (0.36) ALDH1A1HSD17B10ALOX15TSHRL3MBTL1
SCHEMBL2443517 0.82 ALDH1A1 (0.48) MEN1KMT2AALDH1A1HSD17B10ALOX15
SCHEMBL11478124 0.81 ALDH1A1 (0.47) MEN1KMT2AALDH1A1HSD17B10ALOX15
SCHEMBL11721433 0.80 ALDH1A1 (0.43) MEN1KMT2AALDH1A1HSD17B10ALOX15
Aniline SCHEMBL4439642 0.80 ALDH1A1 (0.45) ALDH1A1ALOX15TSHRL3MBTL1TDP1
SCHEMBL11466594 0.79 ALDH1A1 (0.53) MEN1KMT2AALDH1A1HSD17B10ALOX15
SCHEMBL5074350 0.75 ALDH1A1 (0.64) KMT2AALDH1A1HSD17B10ALOX15TSHR
SCHEMBL11729319 0.75 ALDH1A1 (0.50) MEN1KMT2AALDH1A1HSD17B10ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090076206-A1 Additive Mixtures for Agricultural Articles CIBA SPECIALTY CHEMICALS CORP. 2009-03-19 US disclosed
US-7195828-B2 Lubricant for magnetic recording medium and use thereof SHELL OIL COMPANY (US) 2007-03-27 US disclosed
EP-1454316-B1 LUBRICANT FOR MAGNETIC RECORDING MEDIUM AND USE THEREOF PENNZOIL QUAKER STATE CO (US) 2006-08-09 EP disclosed
EP-1454316-A2 LUBRICANT FOR MAGNETIC RECORDING MEDIUM AND USE THEREOF Pennzoil-Quaker State Company (US) 2004-09-08 EP disclosed
WO-2003030151-A2 LUBRICANT FOR MAGNETIC RECORDING MEDIUM AND USE THEREOF PENNZOIL-QUAKER STATE COMPANY (US) 2003-04-10 WO disclosed
US-20020114980-A1 Lubricant for magnetic recording medium and use thereof PENNZOIL-QUAKER STATE COMPANY 2002-08-22 US disclosed
US-6030930-A USEFUL IN LUBRICATING OILS, AND TO CONCENTRATES CONTAINING THE OIL-SOLUBLE DISPERSANT ADDITIVES EXXON CHEMICAL PATENTS INC (US) 2000-02-29 US disclosed
US-6022929-A FUNCTIONALIZATION EXXON CHEMICAL PATENTS INC. (US) 2000-02-08 US disclosed
US-5814715-A LUBRICATING OIL CONCENTRATES; OIL ADDITIVES; DISPERSANTS; POLYMERIZED RAFFINATE II STREAMS USING A LEWIS ACID CATALYST AND BROMINE-CONTAINING PROMOTER EXXON CHEMICAL PATENTS INC (US) 1998-09-29 US disclosed
US-5717039-A CATALYZED REACTION OF ALPHA-OLEFIN ADDITION POLYMER WITH CARBON MONOXIDE AND WATER, ALCOHOL, OR THIOL USING TRANSITION METAL-FREE ACID CATALYST EXXON CHEMICAL PATENTS INC. (US) 1998-02-10 US disclosed
US-5102566-A Diesel fuel additive EXXON CHEMICAL PATENTS INC. (US) 1992-04-07 US disclosed
US-4965005-A Aminomethyl derivatives of monothiocarbamates and dithiocarbamates as additives for lubricants CIBA-GEIGY CORPORATION (US) 1990-10-23 US disclosed
EP-0391651-A2 Improved low ash lubricant composition for internal combustion engines EXXON CHEMICAL PATENTS INC. (US) 1990-10-10 EP disclosed
EP-0391649-A2 Improved ashless lubricant compositions for internal combustion engines EXXON CHEMICAL PATENTS INC. (US) 1990-10-10 EP disclosed
US-4847457-A Methylphosphonic acid amine salt lubricant additives CIBA-GEIGY CORPORATION (US) 1989-07-11 US disclosed
US-4808755-A EXTREME PRESSURE LUBRICANTS CIBA-GEIGY CORPORATION (US) 1989-02-28 US disclosed
US-4778612-A WEAR RESISTANCE; EXTREME PRESSURE LUBRICANTS CIBA-GEIGY CORPORATION (US) 1988-10-18 US disclosed
US-4772405-A ANTIWEAR, EXTREME PRESSURE AND ANTIOXIDANT ADDITIVE FOR SYNTHETIC AND MINERAL LUBRICANTS, ELASTOMERS, HYDRAULIC FLUIDS CIBA-GEIGY CORPORATION (US) 1988-09-20 US disclosed
US-4732691-A HYDROXY AMINES CIBA-GEIGY CORPORATION (US) 1988-03-22 US disclosed
US-4713186-A PHOSPHATE AND GRAPHITE OR INTERCALATION COMPOUND LONZA LTD. (CH) 1987-12-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090076206-A1 Additive Mixtures for Agricultural Articles SOD1, PPOX, CYBB MEN1 3234/4885KMT2A 2672/4885ALDH1A1 1994/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.