Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4429304 | 0.80 | TXNRD1 (0.42) | — | |
| SCHEMBL2541573 | 0.73 | NNMT (0.36) | NNMTPOLBTDP1 | |
| SCHEMBL2541569 | 0.73 | NNMT (0.36) | NNMTPOLBTDP1 | |
| SCHEMBL2541576 | 0.73 | NNMT (0.36) | NNMTPOLBTDP1 | |
| SCHEMBL14358203 | 0.70 | NNMT (0.54) | NNMTPOLBTDP1 | |
| SCHEMBL3058519 | 0.70 | TDP1 (0.51) | NNMTPOLBTDP1 | |
| SCHEMBL4257399 | 0.68 | NPSR1 (0.47) | NNMTPOLBTDP1 | |
| SCHEMBL31663021 | 0.68 | NPSR1 (0.47) | NNMTPOLBTDP1 | |
| SCHEMBL30068099 | 0.68 | NNMT (0.39) | NNMTPOLBTDP1 | |
| SCHEMBL31253850 | 0.66 | NNMT (0.42) | NNMTPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2137195-A1 | TRICYCLIC NITROGEN CONTAINING HETEROCYCLES AS ANTIBACTERIAL AGENTS | Glaxo Group Limited (GB) | 2009-12-30 | — | — | EP | disclosed |
| WO-2008128953-A1 | TRICYCLIC NITROGEN CONTAINING HETEROCYCLES AS ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2008-10-30 | — | — | WO | disclosed |