Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22729274 | 0.74 | CTSK (0.35) | AR | |
| SCHEMBL27899134 | 0.73 | IDO1 (0.36) | MEN1KMT2A | |
| SCHEMBL11067597 | 0.71 | HSD11B1 (0.35) | — | |
| SCHEMBL8177689 | 0.71 | SLC6A2 (0.33) | AR | |
| SCHEMBL9300967 | 0.70 | IDO1 (0.31) | — | |
| SCHEMBL7157390 | 0.70 | HSD11B1 (0.39) | — | |
| SCHEMBL455346 | 0.70 | NOS3 (0.33) | MAPK1 | |
| SCHEMBL27966056 | 0.69 | CTNNB1 (0.30) | — | |
| SCHEMBL10732721 | 0.69 | KCNH2 (0.39) | — | |
| SCHEMBL7945398 | 0.68 | CYP2C19 (0.41) | LMNACYP1A2CYP2C9CYP2C19AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2120896-A1 | MEDICALLY ACTIVE PLASTER | Drossapharm Ag (CH) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008083508-A1 | MEDICALLY ACTIVE PLASTER | DROSSAPHARM AG (CH) | 2008-07-17 | — | — | WO | disclosed |