Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 6/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8840197 | 0.72 | ALDH1A1 (0.42) | KDM4ETDP1ALDH1A1LMNAHPGD | |
| SCHEMBL3289120 | 0.71 | HSD11B1 (0.41) | CYP2C19CYP1A2CYP3A4ALOX15HSD17B10 | |
| SCHEMBL14969341 | 0.70 | IDO1 (0.52) | CYP2C19CYP1A2CYP3A4CLK4ALOX15 | |
| SCHEMBL12817256 | 0.70 | HSD11B1 (0.41) | CYP2C19CYP1A2CYP3A4ALOX15HSD17B10 | |
| SCHEMBL6987649 | 0.70 | HSD11B1 (0.41) | CYP2C19CYP1A2CYP3A4CLK4ALOX15 | |
| SCHEMBL22729274 | 0.68 | CTSK (0.35) | ALDH1A1HSD11B1ARSLC6A2SLC6A4 | |
| SCHEMBL3416823 | 0.68 | HSD11B1 (0.41) | CYP2C19CYP1A2CYP3A4ALOX15HSD17B10 | |
| SCHEMBL4440358 | 0.68 | MEN1 (0.33) | CYP2C19CYP1A2TSHRCYP2C9MAPK1 | |
| SCHEMBL455346 | 0.68 | NOS3 (0.33) | TDP1TRPA1ALDH1A1MAPK1HSD11B1 | |
| SCHEMBL3636361 | 0.68 | HSD11B1 (0.42) | CYP1A2CYP3A4ALOX15TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6307108-B1 | SEPARATING ORGANOPHOSPHORUS LIGAND DEGRADATION PRODUCTS, REACTION BYPRODUCTS AND FORMYLESTER PRODUCTS FROM A REACTION PRODUCT FLUID COMPRISING ONE OR MORE UNREACTED UNSATURATED ESTER REACTANTS | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION | 2001-10-23 | — | — | US | disclosed |
| EP-0073961-B1 | HYDROFORMYLATION PROCESS USING A RHODIUM COMPLEX CATALYST WITH BIPHOSPHINE MONOXIDE LIGANDS | UNION CARBIDE CORPORATION (US) | 1985-08-21 | — | — | EP | disclosed |
| US-4522933-A | Hydroformylation catalyst containing bisphosphine monooxide ligands | UNION CARBIDE CORPORATION (US) | 1985-06-11 | — | — | US | disclosed |
| US-4400548-A | Hydroformylation process using bisphosphine monooxide ligands | UNION CARBIDE CORPORATION (US) | 1983-08-23 | — | — | US | disclosed |
| EP-0073961-A1 | Hydroformylation process using a rhodium complex catalyst with biphosphine monoxide ligands | UNION CARBIDE CORPORATION (US) | 1983-03-16 | — | — | EP | disclosed |