Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.62 |
| ▸ | CCKBR | P32239 | 3/20 | 0.59 |
| ▸ | CCKAR | P32238 | 1/20 | 0.56 |
| ▸ | DPP3 | Q9NY33 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24403862 | 0.91 | CCKBR (0.57) | OPRM1CCKBRCCKARDPP3 | |
| SCHEMBL29648960 | 0.87 | DPP3 (0.69) | OPRM1DPP3 | |
| SCHEMBL30610091 | 0.87 | DPP3 (0.69) | OPRM1DPP3 | |
| SCHEMBL3936861 | 0.85 | MCL1 (0.60) | CCKBRCCKAR | |
| SCHEMBL4440559 | 0.85 | ALOX15 (0.61) | — | |
| SCHEMBL4440562 | 0.85 | ALOX15 (0.61) | — | |
| SCHEMBL30311040 | 0.85 | CCKBR (0.71) | CCKBRCCKAR | |
| SCHEMBL29974089 | 0.84 | DPP3 (0.66) | OPRM1DPP3 | |
| SCHEMBL29772686 | 0.83 | DPP3 (0.65) | OPRM1DPP3 | |
| SCHEMBL29577213 | 0.83 | DPP3 (0.65) | OPRM1DPP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11325944-B2 | Macrocyclic peptides and derivatives thereof with opioid activity | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2022-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11325944-B2 | Macrocyclic peptides and derivatives thereof with opioid activity | OPRL1, OPRM1, OPRK1 | OPRM1 2/4885CCKBR 24/4885CCKAR 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.