Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 1/20 | 0.30 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | DRD1 | P21728 | 3/20 | 0.30 |
| ▸ | DRD5 | P21918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4432464 | 0.87 | DRD1 (0.33) | CYP3A4CYP2D6SMN1; SMN2DRD1DRD5 | |
| SCHEMBL13372899 | 0.83 | MAOA (0.39) | MAOASMN1; SMN2DRD1 | |
| SCHEMBL4582601 | 0.80 | ALDH1A1 (0.38) | MAOAMAOBSLC6A4DRD1DRD5 | |
| SCHEMBL3308515 | 0.79 | ALDH1A1 (0.42) | SMN1; SMN2 | |
| SCHEMBL4431441 | 0.77 | WDR91 (0.41) | CYP2D6MAOAMAOBSLC6A4 | |
| SCHEMBL4432793 | 0.77 | KCNN2 (0.34) | SMN1; SMN2 | |
| SCHEMBL3304805 | 0.74 | ALDH1A1 (0.41) | SMN1; SMN2DRD1 | |
| SCHEMBL4431719 | 0.72 | SLC6A2 (0.31) | SLC6A4 | |
| SCHEMBL13560091 | 0.70 | DRD1 (0.35) | CYP3A4CYP2D6DRD1DRD5 | |
| SCHEMBL3307395 | 0.70 | DRD1 (0.36) | CYP2D6SLC6A4DRD1DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2132193-B1 | SUBSTITUTED PYRROLIDINE AMIDES, THE PRODUCTION THEREOF, AND THE USE THEREOF AS MEDICATIONS | BOEHRINGER INGELHEIM INT (DE) | 2012-10-24 | — | — | EP | disclosed |
| EP-2132193-A1 | SUBSTITUTED PYRROLIDINE AMIDES, THE PRODUCTION THEREOF, AND THE USE THEREOF AS MEDICATIONS | Boehringer Ingelheim International GmbH (DE) | 2009-12-16 | — | — | EP | disclosed |
| WO-2008116881-A1 | SUBSTITUTED PYRROLIDINE AMIDES, THE PRODUCTION THEREOF, AND THE USE THEREOF AS MEDICATIONS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-10-02 | — | — | WO | disclosed |