Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CETP | P11597 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11404737 | 0.81 | ALDH1A1 (0.52) | LTB4R2ALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL14966591 | 0.81 | CPN1 (0.39) | ALDH1A1RAB9A | |
| SCHEMBL4440953 | 0.78 | LTB4R2 (0.43) | LTB4R2ALDH1A1ACHERAB9AHPGD | |
| SCHEMBL6827496 | 0.78 | RAB9A (0.53) | LTB4R2ALDH1A1CETPACHERAB9A | |
| SCHEMBL6831433 | 0.76 | LTB4R2 (0.54) | LTB4R2CETPNR1H4RAB9AMEN1 | |
| SCHEMBL4089396 | 0.76 | CHRM2 (0.52) | LTB4R2ALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL4677800 | 0.75 | LTB4R2 (0.50) | LTB4R2ALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL20893265 | 0.75 | CETP (0.43) | ALDH1A1CETPSLC6A2SLC6A3 | |
| SCHEMBL4734260 | 0.74 | LTB4R2 (0.64) | LTB4R2ALDH1A1CETPNR1H4RAB9A | |
| SCHEMBL5809314 | 0.74 | LTB4R2 (0.41) | LTB4R2ALDH1A1CETPACHERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229033-B1 | 2-Fluoro-(oxid-thiopyran-4-yl)benzene derivatives | UPJOHN CO (US) | 2005-04-20 | — | — | EP | disclosed |
| EP-1149089-B1 | PROCESS TO PREPARE TETRAHYDROTHIOPYRAN-o-FLUORINATED CARBAMATES | UPJOHN CO (US) | 2003-03-26 | — | — | EP | disclosed |
| EP-1229033-A2 | 2-Fluoro-(oxid-thiopyran-4-yl)benzene derivatives | PHARMACIA & UPJOHN COMPANY (US) | 2002-08-07 | — | — | EP | disclosed |
| EP-1149089-A2 | PROCESS TO PREPARE CYCLIC-SULFUR FLUORINE CONTAINING OXAZOLIDINONES | PHARMACIA & UPJOHN COMPANY (US) | 2001-10-31 | — | — | EP | disclosed |
| US-6239283-B1 | BACTERICIDES; REACTING 4-ONE-TETRAHYDROTHIOPYRAN | PHARMACIA & UPJOHN COMPANY | 2001-05-29 | — | — | US | disclosed |
| WO-2000044741-A2 | PROCESS TO PREPARE CYCLIC-SULFUR FLUORINE CONTAINING OXAZOLIDINONES | PHARMACIA & UPJOHN COMPANY (US) | 2000-08-03 | — | — | WO | disclosed |