Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 6/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | WDR5 | P61964 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PRKACA | P17612 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GRK5 | P34947 | 1/20 | 0.40 |
| ▸ | PRKX | P51817 | 1/20 | 0.40 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL44471 | 0.88 | ROCK1 (0.40) | LMNAROCK1ROCK2WDR5MAPT | |
| SCHEMBL44007 | 0.87 | ALDH1A1 (0.41) | LMNAROCK1ROCK2WDR5HTT | |
| SCHEMBL44171 | 0.86 | ROCK1 (0.41) | ROCK1ROCK2WDR5 | |
| SCHEMBL44731 | 0.83 | ROCK1 (0.39) | ROCK1ROCK2WDR5 | |
| SCHEMBL44165 | 0.82 | LMNA (0.48) | LMNAROCK1ROCK2WDR5CYP3A4 | |
| SCHEMBL12951392 | 0.82 | WDR5 (0.41) | ROCK1ROCK2WDR5CYP3A4MAPT | |
| SCHEMBL13844884 | 0.82 | WDR5 (0.41) | LMNAROCK1ROCK2WDR5CYP3A4 | |
| SCHEMBL44338 | 0.82 | WDR5 (0.41) | LMNAROCK1ROCK2WDR5CYP3A4 | |
| SCHEMBL12951391 | 0.82 | WDR5 (0.41) | LMNAROCK1ROCK2WDR5CYP3A4 | |
| SCHEMBL43999 | 0.80 | EGLN2 (0.45) | ROCK1ROCK2WDR5CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011137587-A1 | CYTOKINE INHIBITORS | HUTCHISON MEDIPHARMA LIMITED (CN) | 2011-11-10 | — | — | WO | claimed |
| WO-2011137587-A1 | CYTOKINE INHIBITORS | HUTCHISON MEDIPHARMA LIMITED (CN) | 2011-11-10 | — | — | WO | disclosed |