Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 4/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4053425 | 0.78 | HAO1 (0.39) | — | |
| SCHEMBL6462707 | 0.77 | L3MBTL1 (0.37) | ADRA1DSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL30804967 | 0.73 | IGF1R (0.36) | — | |
| SCHEMBL6479522 | 0.69 | PIK3CA (0.37) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL24090474 | 0.67 | ADRA1D (0.38) | ADRA1DSLC6A2SLC6A4 | |
| SCHEMBL2906600 | 0.67 | CA2 (0.41) | ADRA1DSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28531504 | 0.67 | PTGDR2 (0.40) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13499160 | 0.67 | CA2 (0.41) | ADRA1DSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL12900511 | 0.67 | ADRA1D (0.38) | ADRA1DSLC6A2SLC6A4 | |
| SCHEMBL12651546 | 0.67 | ADRA1D (0.38) | ADRA1DSLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1397137-B1 | HYDANTION DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES | BRISTOL MYERS SQUIBB CO (US) | 2009-10-14 | — | — | EP | disclosed |