Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.65 |
| ▸ | CA12 | O43570 | 1/20 | 0.65 |
| ▸ | CA1 | P00915 | 1/20 | 0.65 |
| ▸ | CA2 | P00918 | 1/20 | 0.65 |
| ▸ | CA9 | Q16790 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL444244 | 1.00 | PTGS2 (0.65) | PTGS2CA12CA1CA2CA9 | |
| SCHEMBL1876228 | 0.93 | PTGS2 (0.65) | PTGS2CA12CA1CA2CA9 | |
| SCHEMBL1876224 | 0.93 | PTGS2 (0.65) | PTGS2CA12CA1CA2CA9 | |
| SCHEMBL8094327 | 0.91 | CA1 (0.76) | PTGS2CA12CA1CA2CA9 | |
| SCHEMBL14164182 | 0.91 | CA1 (0.76) | PTGS2CA12CA1CA2CA9 | |
| SCHEMBL11585495 | 0.86 | PTGS2 (0.69) | PTGS2CA12CA1CA2CA9 | |
| SCHEMBL11585493 | 0.86 | PTGS2 (0.69) | PTGS2CA12CA1CA2CA9 | |
| SCHEMBL11585488 | 0.86 | PTGS2 (0.69) | PTGS2CA12CA1CA2CA9 | |
| SCHEMBL9458165 | 0.83 | PTGS2 (0.66) | PTGS2CA12CA1CA2CA9 | |
| SCHEMBL12972526 | 0.83 | PTGS2 (0.70) | PTGS2CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065430-A1 | Application of Metal Amidoborane and Their Derivatives in Reduction Reaction | DALIAN INSTITUTE OF CHEMICAL PHYSICS, CHINESE ACADEMY OF SCIENCES (CN) | 2012-03-15 | — | — | US | claimed |
| US-4076646-A | O- OR M-TERPHENYLS | HITACHI, LTD. (JA) | 1978-02-28 | — | — | US | claimed |
| US-20220008887-A1 | Swellable Organically Modified Silica as Nanoreactors | APPALACHIAN STATE UNIVERSITY | 2022-01-13 | — | — | US | disclosed |
| WO-2018185675-A1 | SUBSTITUTED OXOAZETIDINE ANALOGUES AS ROR GAMMA MODULATORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2018-10-11 | — | — | WO | disclosed |
| US-20120065430-A1 | Application of Metal Amidoborane and Their Derivatives in Reduction Reaction | DALIAN INSTITUTE OF CHEMICAL PHYSICS, CHINESE ACADEMY OF SCIENCES (CN) | 2012-03-15 | — | — | US | disclosed |
| US-20100143580-A1 | Stabilization of Bicycloheptadiene | AMERICAN AIR LIQUIDE, INC. (US) | 2010-06-10 | — | — | US | disclosed |
| US-RE40795-E1 | Process for producing 5-substituted oxazole compounds and 5-substituted imidazole compounds | NIPPON SODA CO., LTD. (JP) | 2009-06-23 | — | — | US | disclosed |
| US-20070027324-A1 | Process for producing 5-substituted oxazole compounds and 5-substituted imidazole compounds | NIPPON SODA CO., LTD. (JP) | 2007-02-01 | — | — | US | disclosed |
| US-20070027324-A1 | Process for producing 5-substituted oxazole compounds and 5-substituted imidazole compounds | NIPPON SODA CO., LTD. (JP) | 2007-02-01 | — | — | US | disclosed |
| US-4076646-A | O- OR M-TERPHENYLS | HITACHI, LTD. (JA) | 1978-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070027324-A1 | Process for producing 5-substituted oxazole compounds and 5-substituted imidazole compounds | DDT, TES, ALK | PTGS2 2874/4885CA12 1948/4885CA1 671/4885 |
| US-20100143580-A1 | Stabilization of Bicycloheptadiene | DHCR7, CYP8B1, HCCS | PTGS2 1220/4885CA12 2070/4885CA1 3086/4885 |
| US-20220008887-A1 | Swellable Organically Modified Silica as Nanoreactors | MSN, SORD, OGA | PTGS2 3420/4885CA12 688/4885CA1 812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.