⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10932081 | 0.76 | — | — | |
| SCHEMBL5783006 | 0.76 | CES2 (0.32) | — | |
| SCHEMBL8852307 | 0.69 | — | — | |
| SCHEMBL12113778 | 0.68 | CA2 (0.34) | — | |
| SCHEMBL31347875 | 0.63 | CA2 (0.32) | — | |
| SCHEMBL23907061 | 0.63 | MMP8 (0.41) | — | |
| SCHEMBL6328800 | 0.63 | — | — | |
| SCHEMBL6881191 | 0.63 | CES2 (0.31) | — | |
| SCHEMBL7955527 | 0.62 | CES1 (0.43) | — | |
| SCHEMBL9489613 | 0.62 | FDPS (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024006781-A1 | ESTROGEN RECEPTOR ALPHA DEGRADERS AND USE THEREOF | RELAY THERAPEUTICS, INC. (US) | 2024-01-04 | — | — | WO | disclosed |
| WO-2022261069-A1 | METHODS AND TREATMENT OF VIRAL INFECTION WITH SUBSTITUTED PYRAZOLO-PYRIMIDINES | Verge Analytics, Inc. (US) | 2022-12-15 | — | — | WO | disclosed |
| US-20090074757-A1 | Antitumor Combination Comprising Substituted Acryloyl Distamycin Derivatives and Antibodies Inhibiting Growth Factors or Their Receptors | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2009-03-19 | — | — | US | disclosed |
| US-20050272745-A1 | Novel piperidine and piperazine derivatives | ASTRAZENECA AB | 2005-12-08 | — | — | US | disclosed |