Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.38 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3332430 | 0.86 | TTR (0.61) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL5605274 | 0.85 | TTR (0.60) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL4450148 | 0.85 | TTR (0.48) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL5605812 | 0.84 | TTR (0.61) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL8641582 | 0.83 | TTR (0.63) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL8646189 | 0.81 | TTR (0.63) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL11376850 | 0.79 | TTR (0.53) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL688218 | 0.79 | TTR (0.48) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL11406525 | 0.78 | TTR (0.50) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL11366136 | 0.78 | TTR (0.50) | TTRCYP2C9USP2LMNATBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524973-B2 | Nitrate esters of phenylaminothiophenacetic acid derivatives | ALTANA PHARMA AG (US) | 2009-04-28 | — | — | US | disclosed |
| EP-1601663-B1 | NITRATE ESTERS OF PHENYLAMINOTHIOPHENACETIC ACID DERIVATIVES | NYCOMED GMBH (DE) | 2008-12-10 | — | — | EP | disclosed |
| US-20060167082-A1 | Nitrate esters of phenylaminothiophenacetic acid derivatives | ALTANA PHARMA AG (DE) | 2006-07-27 | — | — | US | disclosed |
| EP-1601663-A1 | NITRATE ESTERS OF PHENYLAMINOTHIOPHENACETIC ACID DERIVATIVES | ALTANA Pharma AG (DE) | 2005-12-07 | — | — | EP | disclosed |
| WO-2004074271-A1 | NITRATE ESTERS OF PHENYLAMINOTHIOPHENACETIC ACID DERIVATIVES | ALTANA PHARMA AG (DE) | 2004-09-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060167082-A1 | Nitrate esters of phenylaminothiophenacetic acid derivatives | NOS3, NOS2, NOS1 | TTR 1240/4885CYP2C9 391/4885USP2 2577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.