SCHEMBL444404

SCHEMBL444404

Cc1ccc(OP(Oc2ccccc2)Oc2ccc(C)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
ACHE P22303 3/20 0.48
TSHR P16473 3/20 0.48
LMNA P02545 2/20 0.48
ALOX12 P18054 1/20 0.48
DRD2 P14416 2/20 0.46
DRD4 P21917 2/20 0.46
DRD3 P35462 2/20 0.46
CA4 P22748 1/20 0.42
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
LTA4H P09960 2/20 0.41
HPGD P15428 1/20 0.41
FFAR1 O14842 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
TDP1 Q9NUW8 2/20 0.40
CYP3A4 P08684 1/20 0.39
TEAD4 Q15561 1/20 0.39
PPARG P37231 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL446426 1.00 HTT (0.48) HTTSMN1; SMN2ACHETSHRLMNA
Carbon Monoxide SCHEMBL11762377 0.91 HTT (0.47) HTTSMN1; SMN2ACHETSHRLMNA
SCHEMBL130635 0.89 ACHE (0.55) ACHETSHRLMNADRD2DRD4
SCHEMBL7771299 0.87 ACHE (0.52) ACHETSHRLMNADRD2DRD4
SCHEMBL8650801 0.87 ACHE (0.52) ACHETSHRLMNADRD2DRD4
SCHEMBL4809479 0.87 ACHE (0.52) ACHETSHRLMNADRD2DRD4
SCHEMBL13289 0.87 LTA4H (0.50) ACHETSHRLMNAALOX12CA4
SCHEMBL20710810 0.86 LTA4H (0.41) HTTSMN1; SMN2ACHETSHRLMNA
Iodomethane SCHEMBL1738543 0.84 CA4 (0.46) HTTSMN1; SMN2ACHETSHRLMNA
SCHEMBL3874496 0.84 SMN1; SMN2 (0.44) HTTSMN1; SMN2ACHETSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11760952-B2 Lubricant thickener systems from modified tall oil fatty acids, lubricating compositions, and associated methods INGEVITY SOUTH CAROLINA, LLC (US) 2023-09-19 US disclosed
US-20230097718-A1 BIOBASED EXTREME PRESSURE ADDITIVE FOR LUBRICATING COMPOSITIONS AND ASSOCIATED METHODS INGEVITY SOUTH CAROLINA, LLC 2023-03-30 US disclosed
US-20220220408-A1 LUBRICANT THICKENER SYSTEMS FROM MODIFIED TALL OIL FATTY ACIDS, LUBRICATING COMPOSITIONS, AND ASSOCIATED METHODS MAINSTREAM PINE PRODUCTS, LLC 2022-07-14 US disclosed
EP-3562924-B1 LOW VISCOSITY LUBRICATING OIL COMPOSITIONS FOR TURBOMACHINES EXXONMOBIL RES & ENG CO (US) 2022-05-25 EP disclosed
US-10829708-B2 Composition and method for preventing or reducing engine knock and pre-ignition in high compression spark ignition engines EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2020-11-10 US disclosed
US-10774286-B2 Grease compositions with improved performance and methods of preparing and using the same EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2020-09-15 US disclosed
US-10759741-B2 Separating a solvent from a nickel catalyst by distillation INVISTA NORTH AMERICA S.A R.L. (US) 2020-09-01 US disclosed
EP-3684895-A1 HYDRAULIC OIL COMPOSITIONS WITH IMPROVED HYDROLYTIC AND THERMO-OXIDATIVE STABILITY ExxonMobil Research and Engineering Company (US) 2020-07-29 EP disclosed
WO-2020139333-A1 FORMULATION APPROACH TO EXTEND THE HIGH TEMPERATURE PERFORMANCE OF LITHIUM COMPLEX GREASES EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2020-07-02 WO disclosed
WO-2020131439-A1 GREASE COMPOSITIONS HAVING POLYUREA THICKENERS MADE WITH ISOCYANATE TERMINATED PREPOLYMERS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2020-06-25 WO disclosed
US-6825390-B1 REACTING PHOSPHORUS TRIBROMIDE AND PROPARGYL ALCOHOL AN INERT LIQUID AZEOTROPIC SOLVENT; BROMINATION, DEHYDROXYLATION; SHOCKPROOF, STORAGE STABILITY ALBEMARLE CORPORATION 2004-11-30 US disclosed
US-6777375-B2 WITH EITHER C7-8 SATURATED HYDROCARBONS; A MIXTURE OF C6 AND C9 SATURATED HYDROCARBONS; OR AN ANTIOXIDANT, OR AN ACID SCAVENGER AND ONE OF TOLUENE, XYLENE ISOMERS, ETHER, BETA-IONONE OR ETHANOL; SHOCKPROOF, HEAT RESISTANT ALBEMARLE CORPORATION 2004-08-17 US disclosed
US-20040147617-A1 Stabilization and use of propargyl bromide DEAD SEA BROMINE COMPANY LIMITED (IL) 2004-07-29 US disclosed
WO-2003087024-A1 STABILIZATION AND USE OF PROPARGYL BROMIDE DEAD SEA BROMINE COMPANY LIMITED (IL) 2003-10-23 WO disclosed
US-20030194514-A1 Stabilization and use of propargyl bromide DEAD SEA BROMINE COMPANY LIMITED (IL) 2003-10-16 US disclosed
US-20020010103-A1 Lubricating oil composition having excellent thermal stability, extreme pressure resistance and anti-wear performance CHEVRON ORONITE JAPAN LIMITED (JP) 2002-01-24 US disclosed
EP-1148114-A2 Lubricating oil compositions having excellent thermal stabilty, extreme pressure resistance and anti-wear performance Chevron Oronite Japan Limited (JP) 2001-10-24 EP disclosed
EP-0306094-B1 PROCESS FOR THE HYDROFORMYLATION OF CERTAIN ACRYLIC ACID DERIVATIVES SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1992-01-29 EP disclosed
EP-0306094-A2 Process for the hydroformylation of certain acrylic acid derivatives SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1989-03-08 EP disclosed
US-3948801-A Stabilizer composition of phosphite and lignin WESTVACO CORPORATION (US) 1976-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10759741-B2 Separating a solvent from a nickel catalyst by distillation ALKBH3, IDH3B, IDH3A HTT 1492/4885SMN1; SMN2 2968/4885ACHE 1821/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.