SCHEMBL446426

SCHEMBL446426

Cc1ccc(OP(Oc2ccccc2)Oc2ccccc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
ACHE P22303 3/20 0.48
TSHR P16473 3/20 0.48
LMNA P02545 2/20 0.48
ALOX12 P18054 1/20 0.48
DRD2 P14416 2/20 0.46
DRD4 P21917 2/20 0.46
DRD3 P35462 2/20 0.46
CA4 P22748 1/20 0.42
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
LTA4H P09960 2/20 0.41
HPGD P15428 1/20 0.41
FFAR1 O14842 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
TDP1 Q9NUW8 2/20 0.40
CYP3A4 P08684 1/20 0.39
TEAD4 Q15561 1/20 0.39
PPARG P37231 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL444404 1.00 HTT (0.48) HTTSMN1; SMN2ACHETSHRLMNA
Carbon Monoxide SCHEMBL11762377 0.91 HTT (0.47) HTTSMN1; SMN2ACHETSHRLMNA
SCHEMBL130635 0.89 ACHE (0.55) ACHETSHRLMNADRD2DRD4
SCHEMBL7771299 0.87 ACHE (0.52) ACHETSHRLMNADRD2DRD4
SCHEMBL8650801 0.87 ACHE (0.52) ACHETSHRLMNADRD2DRD4
SCHEMBL4809479 0.87 ACHE (0.52) ACHETSHRLMNADRD2DRD4
SCHEMBL13289 0.87 LTA4H (0.50) ACHETSHRLMNAALOX12CA4
SCHEMBL20710810 0.86 LTA4H (0.41) HTTSMN1; SMN2ACHETSHRLMNA
Iodomethane SCHEMBL1738543 0.84 CA4 (0.46) HTTSMN1; SMN2ACHETSHRLMNA
SCHEMBL3874496 0.84 SMN1; SMN2 (0.44) HTTSMN1; SMN2ACHETSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 177 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0306094-B1 PROCESS FOR THE HYDROFORMYLATION OF CERTAIN ACRYLIC ACID DERIVATIVES SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1992-01-29 EP claimed
EP-0306094-A2 Process for the hydroformylation of certain acrylic acid derivatives SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1989-03-08 EP claimed
US-4198492-A BLEND WITH A STYRENE-TYPE POLYMER, A DIBENZO(C,E)-1,2-OXAPHOSPHORIN AND A PHOSPHITE, A MELAMINE OR A BENZOGUANAMINE ASAHI-DOW LIMITED (JP) 1980-04-15 US claimed
JP-10168228-A None JP disclosed
US-12600833-B2 Cover film FUJIFILM CORPORATION (JP) 2026-04-14 US disclosed
US-20250388773-A1 COVER FILM FUJIFILM CORPORATION (JP) 2025-12-25 US disclosed
WO-2024176739-A1 COVER FILM 富士フイルム株式会社 2024-08-29 WO disclosed
EP-4410544-A1 COVER FILM FUJIFILM Corporation (JP) 2024-08-07 EP disclosed
EP-4410543-A1 COVER FILM FUJIFILM Corporation (JP) 2024-08-07 EP disclosed
US-12054611-B2 Poly(phenylene ether), curable composition containing poly(phenylene ether), dry film, prepreg, cured object, laminate, and electronic component TAIYO HOLDINGS CO., LTD. (JP) 2024-08-06 US disclosed
US-20240255746-A1 COVER FILM FUJIFILM CORPORATION (JP) 2024-08-01 US disclosed
EP-0501440-A1 Composition for refrigerator working fluid use KAO CORPORATION (JP) 1992-09-02 EP disclosed
EP-0475751-A1 Working fluid composition for refrigerating machine Kao Corporation (JP) 1992-03-18 EP disclosed
EP-0306094-B1 PROCESS FOR THE HYDROFORMYLATION OF CERTAIN ACRYLIC ACID DERIVATIVES SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1992-01-29 EP disclosed
EP-0306094-A2 Process for the hydroformylation of certain acrylic acid derivatives SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1989-03-08 EP disclosed
US-4391761-A Process for the production of aryl phosphonyl compounds BAYER AKTIENGESELLSCHAFT (DE) 1983-07-05 US disclosed
US-4377537-A FROM TRIARYL PHOSPHITE AND ALKYL PHOSPHITE OR PHOSPHONOUS ACID DIARYL ESTER AND PHOSPHONOUS ACID DIALKYL ESTER BAYER AKTIENGESELLSCHAFT (DE) 1983-03-22 US disclosed
US-4228064-A CYCLIC PHOSPHORUS-CONTAINING COMPOUNDS ASAKI-DOW LIMITED (JP) 1980-10-14 US disclosed
US-4221700-A POLY(ALKYLATED ALKENYLPHENOL); POLYESTERS OF ALKYLTHIOALKANOIC ACIDS OR ORGANIC PHOSPHITE MARUZEN OIL CO., LTD. (JP) 1980-09-09 US disclosed
US-4198492-A BLEND WITH A STYRENE-TYPE POLYMER, A DIBENZO(C,E)-1,2-OXAPHOSPHORIN AND A PHOSPHITE, A MELAMINE OR A BENZOGUANAMINE ASAHI-DOW LIMITED (JP) 1980-04-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250388773-A1 COVER FILM CDH1, EPCAM, ICAM1 HTT 1674/4885SMN1; SMN2 1503/4885ACHE 1459/4885
US-12600833-B2 Cover film COL2A1, CDH1, COL1A1 HTT 3157/4885SMN1; SMN2 1937/4885ACHE 768/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.