SCHEMBL4444201

SCHEMBL4444201

C(=C/N(c1ccccc1)c1ccccc1)\c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.48
RELA Q04206 1/20 0.46
TRPM8 Q7Z2W7 2/20 0.45
ALDH1A1 P00352 2/20 0.41
LMNA P02545 2/20 0.41
NFE2L2 Q16236 2/20 0.41
CYP19A1 P11511 2/20 0.41
MAOA P21397 2/20 0.41
TRPA1 O75762 2/20 0.41
ALOX5 P09917 1/20 0.41
MAPK1 P28482 1/20 0.41
HDAC3 O15379 1/20 0.39
TNKS O95271 1/20 0.39
HDAC4 P56524 1/20 0.39
HDAC1 Q13547 1/20 0.39
HCAR2 Q8TDS4 1/20 0.39
HDAC7 Q8WUI4 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC10 Q969S8 1/20 0.39
HDAC11 Q96DB2 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL988301 1.00 MAOB (0.48) MAOBRELATRPM8ALDH1A1LMNA
Benzene SCHEMBL6405642 1.00 MAOB (0.48) MAOBRELATRPM8ALDH1A1LMNA
SCHEMBL27986727 0.87 RELA (0.45) MAOBRELATRPM8ALDH1A1LMNA
SCHEMBL1568910 0.86 RELA (0.41) MAOBRELATRPM8ALDH1A1TRPA1
SCHEMBL30561199 0.85 CYP1B1 (0.41) MAOBRELATRPM8ALDH1A1LMNA
SCHEMBL2492787 0.85 TRPM8 (0.53) RELATRPM8ALDH1A1LMNANFE2L2
SCHEMBL30561206 0.85 ALDH1A1 (0.50) MAOBRELATRPM8ALDH1A1LMNA
SCHEMBL17255707 0.85 TRPM8 (0.53) RELATRPM8ALDH1A1LMNANFE2L2
SCHEMBL30561197 0.85 NFE2L2 (0.59) MAOBRELAALDH1A1NFE2L2MAOA
SCHEMBL3282954 0.85 RELA (0.48) MAOBRELATRPM8ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117701325-B Non-sulfur-chlorine system stainless steel cold rolling oil and preparation method and test method thereof 超滑科技(佛山)有限责任公司 2024-07-16 CN claimed
CN-117701325-A Non-sulfur-chlorine system stainless steel cold rolling oil and preparation method and test method thereof 超滑科技(佛山)有限责任公司 2024-03-15 CN claimed
CN-119875285-A Low-emission polyolefin composite material and preparation method and application thereof 上海金发科技发展有限公司 2025-04-25 CN disclosed
CN-114907900-B Automatic gearbox oil, I-type metal cutting fluid and novel lubricating oil 东莞市嘉丰润滑科技有限公司 2023-07-21 CN disclosed
CN-114302941-B Grease composition for constant velocity joints comprising zinc sulphide and molybdenum disulphide and/or tungsten disulphide GKN动力传动国际有限公司 2023-04-04 CN disclosed
CN-114630887-B Grease composition for constant velocity joints comprising zinc and copper sulphide and molybdenum and/or tungsten disulphide GKN动力传动国际有限公司 2023-02-17 CN disclosed
CN-114630887-A Grease composition for constant velocity joints comprising zinc and copper sulphide and molybdenum and/or tungsten disulphide GKN动力传动国际有限公司 2022-06-14 CN disclosed
CN-114302941-A Grease composition for constant velocity joints comprising zinc sulphide and molybdenum disulphide and/or tungsten disulphide GKN动力传动国际有限公司 2022-04-08 CN disclosed
US-20180022693-A1 COMPOUNDS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2018-01-25 US disclosed
US-20180022693-A1 COMPOUNDS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2018-01-25 US disclosed
WO-2017106930-A1 COMPOUNDS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2017-06-29 WO disclosed
EP-2782921-A1 ORGANIC TUNGSTEN COMPLEXES Vanderbilt Chemicals, LLC (US) 2014-10-01 EP disclosed
WO-2013077948-A1 ORGANIC TUNGSTEN COMPLEXES VANDERBILT CHEMICALS, LLC. (US) 2013-05-30 WO disclosed
EP-2137199-A1 ORGANIC TUNGSTEN COMPLEXES R.T. Vanderbilt Company, Inc. (US) 2009-12-30 EP disclosed
WO-2008116099-A1 ORGANIC TUNGSTEN COMPLEXES R.T. VANDERBILT COMPANY, INC. (US) 2008-09-25 WO disclosed
EP-1853684-A2 METHOD FOR IMPROVING THE OXIDATIVE STABILITY OF INDUSTRIAL FLUIDS Chemtura Corporation (US) 2007-11-14 EP disclosed
WO-2006094138-A2 METHOD FOR IMPROVING THE OXIDATIVE STABILITY OF INDUSTRIAL FLUIDS CHEMTURA CORPORATION (US) 2006-09-08 WO disclosed
WO-2004094572-A2 COMBINATIONS OF ANTI-OXIDANTS AND BIOCIDES IN METAL WORKING FLUIDS CHEMTURA CORPORATION (US) 2004-11-04 WO disclosed
EP-1406912-A1 ORGANOMOLYBDENUM COMPLEXES AS FRICTION MODIFIERS Crompton Corporation (US) 2004-04-14 EP disclosed
WO-2003008428-A1 ORGANOMOLYBDENUM COMPLEXES AS FRICTION MODIFIERS CROMPTON CORPORATION (US) 2003-01-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180022693-A1 COMPOUNDS ERCC4, NQO1, ERCC5 MAOB 1176/4885RELA 2376/4885TRPM8 1534/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.