Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.34 |
| ▸ | UBE2N | P61088 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8654184 | 0.82 | GAA (0.47) | ALDH1A1GAAKDM4ESRCHSD17B10 | |
| SCHEMBL9418516 | 0.81 | RAD51 (0.50) | ALDH1A1GAAKDM4ESRCHSD17B10 | |
| Water SCHEMBL11384196 | 0.81 | GAA (0.46) | ALDH1A1GAAKDM4ESRCHSD17B10 | |
| SCHEMBL9418518 | 0.81 | GAA (0.46) | ALDH1A1GAAKDM4ESRCHSD17B10 | |
| SCHEMBL12593470 | 0.80 | SMN1; SMN2 (0.52) | ALDH1A1ERN1NPC1LMNA | |
| SCHEMBL12153861 | 0.79 | ALDH1A1 (0.39) | ALDH1A1GAAKDM4ESRCHSD17B10 | |
| SCHEMBL1793926 | 0.78 | ERN1 (0.46) | ALDH1A1ERN1CYP2A6CA1CA2 | |
| SCHEMBL6076943 | 0.78 | KDM4E (0.41) | ALDH1A1KDM4EERN1 | |
| SCHEMBL14735611 | 0.78 | RAD51 (0.49) | ALDH1A1ERN1L3MBTL1LMNAKMT2A | |
| SCHEMBL2600014 | 0.78 | TDP1 (0.53) | ALDH1A1KDM4EERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015106164-A1 | LXR AGONISTS AND USES THEREOF | RGENIX, INC. (US) | 2015-07-16 | — | — | WO | disclosed |
| US-20090209605-A1 | NEMATICIDAL COMPOSITIONS | DEVGEN N.V. (BE) | 2009-08-20 | — | — | US | disclosed |
| US-20080146445-A1 | Nematicidal Compositions | DEVGEN NV (BE) | 2008-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209605-A1 | NEMATICIDAL COMPOSITIONS | ACHE, DNPH1, NANP | ALDH1A1 4082/4885GAA 1884/4885KDM4E 1146/4885 |
| US-20080146445-A1 | Nematicidal Compositions | ACHE, DNPH1, NANP | ALDH1A1 4082/4885GAA 1884/4885KDM4E 1146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.