Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD51 | Q06609 | 1/20 | 0.49 |
| ▸ | ERN1 | O75460 | 4/20 | 0.46 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | TYR | P14679 | 2/20 | 0.31 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.31 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4444489 | 0.78 | ALDH1A1 (0.42) | ERN1L3MBTL1ALDH1A1LMNAKMT2A | |
| SCHEMBL12593470 | 0.78 | SMN1; SMN2 (0.52) | ERN1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL2600014 | 0.77 | TDP1 (0.53) | ERN1CCR2ALDH1A1TDP1MCL1 | |
| SCHEMBL1793926 | 0.77 | ERN1 (0.46) | ERN1CCR2ALDH1A1SMN1; SMN2 | |
| SCHEMBL6076943 | 0.77 | KDM4E (0.41) | ERN1CCR2ALDH1A1 | |
| SCHEMBL9185083 | 0.74 | CYP2A6 (0.42) | L3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL18254534 | 0.74 | L3MBTL1 (0.44) | RAD51CCR2L3MBTL1ALDH1A1TDP1 | |
| SCHEMBL122510 | 0.73 | RAD51 (0.53) | RAD51SMN1; SMN2CASP3 | |
| SCHEMBL4556987 | 0.73 | ALOX5AP (0.41) | L3MBTL1ALDH1A1SMN1; SMN2MEN1LMNA | |
| SCHEMBL30487705 | 0.73 | ALOX5AP (0.41) | L3MBTL1ALDH1A1SMN1; SMN2MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2565182-B1 | NOVEL AMIDE DERIVATIVE AND USE THEREOF AS MEDICINE | MITSUBISHI TANABE PHARMA CORP (JP) | 2017-10-11 | — | — | EP | disclosed |
| EP-2565182-A1 | NOVEL AMIDE DERIVATIVE AND USE THEREOF AS MEDICINE | Mitsubishi Tanabe Pharma Corporation (JP) | 2013-03-06 | — | — | EP | disclosed |