SCHEMBL444478

SCHEMBL444478

c1ccc(C2=C(c3ccccc3)N2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.53
HSD17B10 Q99714 3/20 0.41
ALOX15 P16050 1/20 0.41
MAPK1 P28482 2/20 0.40
RAB9A P51151 2/20 0.40
NPC1 O15118 1/20 0.40
KDM4E B2RXH2 1/20 0.39
PLA2G10 O15496 1/20 0.39
GAA P10253 1/20 0.39
HPGD P15428 1/20 0.39
CYP1A2 P05177 1/20 0.38
LMNA P02545 1/20 0.38
MAPT P10636 1/20 0.38
HTT P42858 1/20 0.38
CYP3A4 P08684 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
NOTUM Q6P988 1/20 0.38
MMP3 P08254 1/20 0.38
BCL2L1 Q07817 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7107009 0.97 ALDH1A1 (0.50) ALDH1A1HSD17B10ALOX15MAPK1RAB9A
SCHEMBL4580148 0.82 ALDH1A1 (0.46) ALDH1A1HSD17B10MAPK1HPGDTDP1
SCHEMBL2718825 0.80 ABL1 (0.43) ALDH1A1KDM4EHPGDMAPTCYP3A4
Biphenyl SCHEMBL27643334 0.72 ALDH1A1 (0.82) ALDH1A1HSD17B10MAPK1RAB9ANPC1
SCHEMBL30108088 0.71 ALDH1A1 (1.00) ALDH1A1HSD17B10MAPK1RAB9ANPC1
Biphenyl SCHEMBL1358618 0.71 ALDH1A1 (1.00) ALDH1A1HSD17B10MAPK1RAB9ANPC1
Biphenyl SCHEMBL29008551 0.71 ALDH1A1 (1.00) ALDH1A1HSD17B10MAPK1RAB9ANPC1
Biphenyl SCHEMBL2548048 0.71 ALDH1A1 (1.00) ALDH1A1HSD17B10MAPK1RAB9ANPC1
Biphenyl SCHEMBL28890607 0.71 ALDH1A1 (1.00) ALDH1A1HSD17B10MAPK1RAB9ANPC1
Biphenyl SCHEMBL164 0.71 ALDH1A1 (1.00) ALDH1A1HSD17B10MAPK1RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1059 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4612298-A1 BCMA VH-ONLY CARS Dana-Farber Cancer Institute, Inc. (US) 2025-09-10 EP claimed
CN-120040347-A Preparation method of oxcarbazepine impurity 重庆圣华曦药业股份有限公司 2025-05-27 CN claimed
CN-119798163-A New continuous carbamazepine preparation process 浙江工业大学 2025-04-11 CN claimed
CN-117050016-B Preparation method of carbamazepine intermediate 江苏慈星药业有限公司 2025-03-28 CN claimed
CN-119264051-A Preparation method of key intermediate of dibenzoazepine medicines and intermediate thereof 浙江中科创越药业有限公司 2025-01-07 CN claimed
CN-116284148-B Asymmetric catalyst of macromolecule supported metal rhodium and synthetic method thereof 哈尔滨工业大学(深圳) 2024-12-24 CN claimed
CN-118638054-A Comprehensive synthesis method of iminostilbene and intermediate thereof 湖北华洲药业有限公司 2024-09-13 CN claimed
CN-118388406-A Double-response iminostilbene fluorescent probe as well as preparation method and application thereof 天津大学 2024-07-26 CN claimed
CN-118388456-A Iminostilbene fluorescent probe for detecting hydrazine hydrate and preparation method and application thereof 天津大学 2024-07-26 CN claimed
US-20240216316-A1 DIHOMO-GAMMA LINOLENIC ACID (DGLA) IS A NOVEL SENOLYTIC BUCK INST RES AGING (US) 2024-07-04 US claimed
WO-1994012621-A1 ENHANCEMENT OF ENZYME REACTIONS NOVO NORDISK (DK) 1994-06-09 WO claimed
EP-0546563-A2 Complex crystal TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 1993-06-16 EP claimed
US-5110923-A METHOD FOR PREPARING 5-CHLOROCARBONYL-5H-DIBENZ(B,F)AZEPINE ARZNEIMITTELWERK DRESDEN GMBH (DE) 1992-05-05 US claimed
EP-0237952-B1 PROCESS FOR THE PREPARATION OF 5H-DIBENZO-(B, F)-AZEPINE ORION-YHTYMÄ OY FERMION (FI) 1991-10-30 EP claimed
CN-1039018-A N, the preparation method of N-(the inferior second triolefin of dibenzo) urea CIBA GEIGY AG (CH) 1990-01-24 CN claimed
US-4847374-A Process for the manufacture of N,N-(Dibenzohexatrienylene)ureas CIBA-GEIGY CORPORATION (US) 1989-07-11 US claimed
US-4758554-A Method for treating convulsions and epilepsy with organic copper compounds INTERNATIONAL COPPER RESEARCH ASSOCIATION (US) 1988-07-19 US claimed
US-4699634-A SEMIPERMEABLE MEMBRANES THE STANDARD OIL COMPANY (US) 1987-10-13 US claimed
EP-0237952-A1 Process for the preparation of 5H-Dibenzo-(b, f)-azepine ORION-YHTYMÄ OY FERMION (FI) 1987-09-23 EP claimed
EP-0063525-A1 Dibenzazepine tetracyclic derivatives, process for their preparation and pharmaceutical compositions containing them CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1982-10-27 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240216316-A1 DIHOMO-GAMMA LINOLENIC ACID (DGLA) IS A NOVEL SENOLYTIC DAGLA, DAGLB, MGLL ALDH1A1 978/4885HSD17B10 860/4885ALOX15 29/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.