SCHEMBL4444843

SCHEMBL4444843

Cc1cc(C(=O)c2ccccc2)cc(C)c1O.O=C(O)CNCC(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.47
GABRB1 P18505 1/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
NPC1 O15118 1/20 0.47
ALDH1A1 P00352 3/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
THRB P10828 1/20 0.43
L3MBTL1 Q9Y468 3/20 0.43
ATM Q13315 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
CNR1 P21554 1/20 0.42
CNR2 P34972 1/20 0.42
BCL2L1 Q07817 1/20 0.41
CES2 O00748 1/20 0.40
CES1 P23141 1/20 0.40
TTR P02766 1/20 0.40
HTT P42858 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9618894 0.87 GABRA1 (0.59) GABRA1GABRB1MEN1KMT2ANPC1
SCHEMBL8095440 0.80 THRB (0.37) MEN1KMT2ANPC1ALDH1A1CYP2C9
SCHEMBL9000998 0.79 SRC (0.44) ALDH1A1CYP2C19THRBL3MBTL1ATM
SCHEMBL10809054 0.78 GAA (0.42) MEN1KMT2AALDH1A1CYP2C9L3MBTL1
SCHEMBL9306415 0.78 ALDH1A1 (0.43) MEN1KMT2AALDH1A1CYP2C9CYP2C19
SCHEMBL9323609 0.77 ALDH1A1 (0.61) GABRA1GABRB1MEN1KMT2ANPC1
SCHEMBL10350236 0.77 HTT (0.61) GABRA1GABRB1MEN1KMT2ANPC1
SCHEMBL5712263 0.77 GABRA1 (0.53) GABRA1GABRB1MEN1KMT2AALDH1A1
SCHEMBL11151289 0.76 ATM (0.56) GABRA1GABRB1MEN1KMT2ANPC1
SCHEMBL10421181 0.76 KMT2A (0.51) GABRA1GABRB1MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9377433-B2 Accurate integrated low-cost electrode chips for point-of-need analysis and a method of utilization in hot electron-induced electrochemiluminescent systems LABMASTER OY (FI) 2016-06-28 US disclosed
EP-1864117-B1 CONDUCTOR/INSULATOR/POROUS FILM-DEVICE AND ASSOCIATED ELECTROCHEMILUMINESCENCE-BASED ANALYTICAL METHOD LABMASTER LTD (FI) 2015-10-14 EP disclosed
US-20130206611-A1 Accurate Integrated Low-Cost Electrode Chips for Point-Of-Need Analysis and A Method of Utilization in Hot Electron-Induced Electrochemiluminescent Systems LABMASTER OY (FI) 2013-08-15 US disclosed
EP-2580579-A1 ACCURATE INTEGRATED LOW-COST ELECTRODE CHIPS FOR POINT- OF-NEED ANALYSIS AND A METHOD OF UTILIZATION IN HOT ELECTRON-INDUCED ELECTROCHEMILUMINESCENT SYSTEMS Labmaster Oy (FI) 2013-04-17 EP disclosed
US-8382968-B2 Conductor/insulator/porous film-device and its use with the electrochemiluminescence-based analytical methods LABMASTER LTD. (FI) 2013-02-26 US disclosed
US-20090178924-A1 Conductor/Insulator/Porous Film-Device and Its Use With the Electrochemiluminescence-Based Analytical Methods LABMASTER LTD. (FI) 2009-07-16 US disclosed
EP-1204858-B1 METHOD FOR ELECTROLUMINESCENCE MEASUREMENTS ORION DIAGNOSTICA OY (FI) 2008-05-07 EP disclosed
EP-1864117-A1 CONDUCTOR/INSULATOR/POROUS FILM-DEVICE AND ITS USE WITH THE ELECTROCHEMILUMINESCENCE-BASED ANALYTICAL METHODS Labmaster Ltd (FI) 2007-12-12 EP disclosed
WO-2006103313-A1 CONDUCTOR/INSULATOR/POROUS FILM-DEVICE AND ITS USE WITH THE ELECTROCHEMILUMINESCENCE-BASED ANALYTICAL METHODS LABMASTER LTD (FI) 2006-10-05 WO disclosed
EP-1204858-A2 METHOD FOR LUMINESCENCE MEASUREMENTS ORION-YHTYMÄ OY (FI) 2002-05-15 EP disclosed
WO-2001013095-A1 METHOD FOR LUMINESCENCE MEASUREMENTS Orion-Yhtymä Oyj (FI) 2001-02-22 WO disclosed
US-6136268-A Method for luminescence measurements ORION DIAGNOSTICA (FI) 2000-10-24 US disclosed
EP-0544662-B1 ENZYME AMPLIFIED LANTHANIDE CHELATE LUMINESCENCE ASSAY KRONEM SYSTEMS INC (CA) 1996-09-18 EP disclosed
US-5262299-A Salicyl phosphate substrates, high sensitivity KRONEM SYSTEMS, INC. (CA) 1993-11-16 US disclosed
EP-0544662-A1 ENZYME AMPLIFIED LANTHANID CHELATE LUMINESCENCE ASSAY. KRONEM SYSTEMS INC (CA) 1993-06-09 EP disclosed
WO-1991008490-A1 ENZYME AMPLIFIED LANTHANID CHELATE LUMINESCENCE ASSAY KRONEM SYSTEMS INC. (CA) 1991-06-13 WO disclosed