SCHEMBL5712263

SCHEMBL5712263

Cc1cc(C(=O)c2ccccc2)cc(C(=O)c2ccccc2)c1O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.53
GABRB1 P18505 1/20 0.53
BCL2 P10415 1/20 0.53
MCL1 Q07820 1/20 0.53
ALDH1A1 P00352 3/20 0.50
ATM Q13315 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
KDM4E B2RXH2 3/20 0.47
KMT2A Q03164 2/20 0.47
MEN1 O00255 1/20 0.47
USP2 O75604 1/20 0.47
GAA P10253 1/20 0.47
KEAP1 Q14145 1/20 0.47
NFE2L2 Q16236 1/20 0.47
CNR1 P21554 1/20 0.46
CNR2 P34972 1/20 0.46
MAPT P10636 2/20 0.46
MAPK1 P28482 2/20 0.46
HSD17B10 Q99714 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10421181 0.91 KMT2A (0.51) GABRA1GABRB1ALDH1A1ATMTDP1
SCHEMBL9618894 0.89 GABRA1 (0.59) GABRA1GABRB1ALDH1A1ATMTDP1
SCHEMBL2861855 0.86 LMNA (0.53) GABRA1GABRB1BCL2MCL1ALDH1A1
SCHEMBL8680650 0.84 BCL2 (0.68) GABRA1GABRB1BCL2MCL1ALDH1A1
SCHEMBL24354139 0.83 BCL2 (0.50) GABRA1GABRB1BCL2MCL1ALDH1A1
SCHEMBL2865160 0.82 BCL2 (0.53) GABRA1GABRB1BCL2MCL1ALDH1A1
SCHEMBL28858093 0.81 MEN1 (0.59) GABRA1GABRB1BCL2MCL1ALDH1A1
SCHEMBL1666973 0.81 ALDH1A1 (0.58) GABRA1GABRB1ALDH1A1ATMTDP1
SCHEMBL12337417 0.79 ALDH1A1 (0.61) ALDH1A1ATMTDP1L3MBTL1KDM4E
SCHEMBL3140205 0.79 BCL2 (0.57) GABRA1GABRB1BCL2MCL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1266924-B1 Polycarbonates and polyestercarbonates having branched endgroups BAYER MATERIALSCIENCE AG (DE) 2006-06-28 EP claimed
US-6784278-B2 USING PHENOLS HAVING A BRANCHED STRUCTURE AS TERMINAL GROUPS IN POLYCARBONATES, POLYESTER CARBONATES AND POLYESTERS BAYER AKTIENGESELLSCHAFT (DE) 2004-08-31 US claimed
US-20030096941-A1 Polycarbonates, polyester carbonates and polyesters having branched terminal groups BAYER AKTIENGESELLSCHAFT (DE) 2003-05-22 US claimed
EP-1266924-A2 Polycarbonates, polyestercarbonates and polyesters having branched endgroups BAYER AG (DE) 2002-12-18 EP claimed
CN-100354335-C Method of using phenol, polymer resin produced by the method, and molded article containing the polymer resin BAYER AG (DE) 2007-12-12 CN disclosed
CN-1880296-A Phenols having branched structure BAYER AG (DE) 2006-12-20 CN disclosed
EP-1266924-B1 Polycarbonates and polyestercarbonates having branched endgroups BAYER MATERIALSCIENCE AG (DE) 2006-06-28 EP disclosed
US-6784278-B2 USING PHENOLS HAVING A BRANCHED STRUCTURE AS TERMINAL GROUPS IN POLYCARBONATES, POLYESTER CARBONATES AND POLYESTERS BAYER AKTIENGESELLSCHAFT (DE) 2004-08-31 US disclosed
US-20030096941-A1 Polycarbonates, polyester carbonates and polyesters having branched terminal groups BAYER AKTIENGESELLSCHAFT (DE) 2003-05-22 US disclosed
CN-1390872-A polycarbonates, polyester carbonates and polyesters having branched end groups BAYER AG (DE) 2003-01-15 CN disclosed
EP-1266924-A2 Polycarbonates, polyestercarbonates and polyesters having branched endgroups BAYER AG (DE) 2002-12-18 EP disclosed