SCHEMBL4444922

SCHEMBL4444922

CCN(C)C(C)(C)C(N)=O

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19369917 0.77 ALDH1A1 (0.32)
SCHEMBL10207226 0.77 TSHR (0.36) LMNA
SCHEMBL6944552 0.77 LMNA (0.31) LMNAHSD17B10
SCHEMBL22788853 0.76
SCHEMBL22828145 0.76 LMNA (0.30) LMNA
SCHEMBL26723718 0.75 CNR2 (0.30)
Hydrochloric Acid SCHEMBL11819437 0.75 LMNA (0.30) LMNAHSD17B10
SCHEMBL4452432 0.73
SCHEMBL19151297 0.71 ALOX15 (0.32)
SCHEMBL31618685 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3888691-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LIKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS Hangzhou Dac Biotech Co., Ltd. (CN) 2021-10-06 EP disclosed
CN-101528706-A Pyrazole compounds NAT HEALTH RESEARCH INSTITUTES (CN) 2009-09-09 CN disclosed
EP-2084135-A2 PYRAZOLE COMPOUNDS National Health Research Institutes (TW) 2009-08-05 EP disclosed
US-20090042864-A2 PYRAZOLE COMPOUNDS NATIONAL HEALTH RESEARCH INSTITUTES (TW) 2009-02-12 US disclosed
WO-2008060771-A2 PYRAZOLE COMPOUNDS NATIONAL HEALTH RESEARCH INSTITUTES (TW) 2008-05-22 WO disclosed
US-20080090809-A1 PYRAZOLE COMPOUNDS NATIONAL HEALTH RESEARCH INSTITUTES (TW) 2008-04-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090042864-A2 PYRAZOLE COMPOUNDS CNR2, CNR1, GPR18 LMNA 4767/4885HSD17B10 2120/4885
US-20080090809-A1 PYRAZOLE COMPOUNDS CNR2, CNR1, GPR18 LMNA 4767/4885HSD17B10 2120/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.