Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 7/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MPL | P40238 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4451026 | 1.00 | RARB (0.44) | RARBSMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL4444137 | 0.94 | HSD11B1 (0.40) | RARBSMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL4451024 | 0.91 | SPHK1 (0.41) | RARBSMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL4451022 | 0.91 | SPHK1 (0.41) | RARBSMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL6058898 | 0.89 | TLR8 (0.43) | RARBSMN1; SMN2RAB9ATSHRTP53 | |
| SCHEMBL28830953 | 0.88 | RARB (0.44) | RARBSMN1; SMN2RAB9ATSHRTP53 | |
| SCHEMBL19410763 | 0.85 | HSD11B1 (0.43) | RARBSMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL15673109 | 0.82 | PSMB5 (0.42) | RARBSMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL10058068 | 0.80 | RARB (0.39) | RARBSMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL4449698 | 0.78 | PSMB5 (0.40) | RARBSMN1; SMN2NPC1RAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090179196-A1 | Pyrene-Based Organic Compound, Transistor Material and Light-Emitting Transistor Device | KYUSHU UNIVERSITY (JP) | 2009-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090179196-A1 | Pyrene-Based Organic Compound, Transistor Material and Light-Emitting Transistor Device | PPOX, JUP, TARDBP | RARB 829/4885SMN1; SMN2 4684/4885NPC1 1863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.