Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | RARB | P10826 | 3/20 | 0.38 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | MPL | P40238 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4451024 | 1.00 | SPHK1 (0.41) | SPHK1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4451026 | 0.91 | RARB (0.44) | RARBNPC1RAB9AMPLSMN1; SMN2 | |
| SCHEMBL4444985 | 0.91 | RARB (0.44) | RARBNPC1RAB9AMPLSMN1; SMN2 | |
| SCHEMBL4444137 | 0.85 | HSD11B1 (0.40) | CYP3A4RARBNPC1RAB9AMPL | |
| SCHEMBL4449928 | 0.82 | GRIN2D (0.41) | SPHK1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL3478454 | 0.82 | GRIN2D (0.41) | SPHK1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL3478453 | 0.82 | GRIN2D (0.41) | SPHK1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4449932 | 0.82 | GRIN2D (0.41) | SPHK1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6058898 | 0.81 | TLR8 (0.43) | CYP3A4RARBRAB9ASMN1; SMN2TP53 | |
| SCHEMBL28830953 | 0.80 | RARB (0.44) | CYP3A4RARBRAB9ASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090179196-A1 | Pyrene-Based Organic Compound, Transistor Material and Light-Emitting Transistor Device | KYUSHU UNIVERSITY (JP) | 2009-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090179196-A1 | Pyrene-Based Organic Compound, Transistor Material and Light-Emitting Transistor Device | PPOX, JUP, TARDBP | SPHK1 4772/4885GRIN2D 2081/4885GRIN3B 2771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.