SCHEMBL4445241

SCHEMBL4445241

C=CC(O)c1cccc(Cl)c1O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.42
KIF11 P52732 1/20 0.38
TSHR P16473 2/20 0.34
CYP1A2 P05177 2/20 0.34
CYP3A4 P08684 2/20 0.34
LMNA P02545 2/20 0.34
HPGD P15428 2/20 0.34
HIF1A Q16665 2/20 0.34
FAAH O00519 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
GABRA1 P14867 1/20 0.34
GABRB1 P18505 1/20 0.34
GABRG2 P18507 1/20 0.34
PTGS1 P23219 1/20 0.34
SLC6A2 P23975 1/20 0.34
HTR2C P28335 1/20 0.34
GABRB3 P28472 1/20 0.34
GABRA5 P31644 1/20 0.34
GABRA3 P34903 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11405118 0.86 GABRA1 (0.46) ALDH1A1KIF11TSHRCYP1A2CYP3A4
SCHEMBL11672242 0.82 ALDH1A1 (0.52) ALDH1A1TSHRCYP3A4LMNAHIF1A
SCHEMBL11789192 0.80 LMNA (0.44) ALDH1A1KIF11TSHRCYP1A2CYP3A4
SCHEMBL4108154 0.79 ALDH1A1 (0.41) ALDH1A1CYP1A2CYP3A4LMNAHPGD
SCHEMBL15771491 0.79 ALDH1A1 (0.41) ALDH1A1KIF11CYP1A2CYP3A4LMNA
SCHEMBL6119421 0.79 ALDH1A1 (0.41) ALDH1A1KIF11CYP1A2CYP3A4LMNA
SCHEMBL4444306 0.77 LMNA (0.34) TSHRCYP1A2CYP3A4LMNAHPGD
SCHEMBL2542973 0.77 ALDH1A1 (0.48) ALDH1A1TSHRCYP1A2CYP3A4LMNA
SCHEMBL4446280 0.77 ERN1 (0.46) TSHRCYP1A2CYP3A4LMNAHPGD
SCHEMBL7594286 0.74 ALDH1A1 (0.39) ALDH1A1TSHRGABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101151234-B Process for producing cyclopropylphenol derivative SANKYO AGRO CO LTD 2011-06-15 CN disclosed
US-7629494-B2 Process for producing cyclopropylphenol derivative MITSUI CHEMICALS AGRO, INC. (JP) 2009-12-08 US disclosed
US-20090054681-A1 Production Process of cyclopropylphenol derivatives SANKYO AGRO COMPANY, LIMITED (JP) 2009-02-26 US disclosed
CN-101151234-A Process for producing cyclopropylphenol derivative SANKYO AGRO CO LTD (JP) 2008-03-26 CN disclosed
EP-1880987-A1 PROCESS FOR PRODUCING CYCLOPROPYLPHENOL DERIVATIVE Sankyo Agro Company, Limited (JP) 2008-01-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054681-A1 Production Process of cyclopropylphenol derivatives CBR3, CYP4X1, CYP4A11 ALDH1A1 2052/4885KIF11 1913/4885TSHR 249/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.