SCHEMBL4445357

SCHEMBL4445357

CCCCC1(c2ccc(OC)cc2)C(=O)Oc2ccccc21

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 6/20 0.42
MMP9 P14780 6/20 0.42
MMP8 P22894 3/20 0.42
MMP13 P45452 3/20 0.42
MMP3 P08254 2/20 0.42
ACHE P22303 1/20 0.37
SCN9A Q15858 3/20 0.36
NPSR1 Q6W5P4 2/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
ALDH1A1 P00352 2/20 0.35
MAPT P10636 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
FFAR1 O14842 1/20 0.33
PTGS2 P35354 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1828711 0.89 MMP2 (0.41) MMP2MMP9MMP8MMP13MMP3
SCHEMBL31036709 0.87 ACHE (0.37) MMP2MMP9MMP3ACHESCN9A
SCHEMBL4449571 0.87 MMP2 (0.48) MMP2MMP9MMP8MMP13MMP3
SCHEMBL7530635 0.85 MEN1 (0.39) MMP2MMP9MMP8MMP13MMP3
SCHEMBL27807661 0.82 BDKRB2 (0.39) MMP2MMP9MMP8MMP13MMP3
SCHEMBL3896300 0.82 MMP2 (0.56) MMP2MMP9MMP8MMP13MMP3
SCHEMBL3897034 0.82 MMP2 (0.56) MMP2MMP9MMP8MMP13MMP3
SCHEMBL1557114 0.80 SCN9A (0.35) MMP2MMP9MMP8MMP13MMP3
SCHEMBL28813338 0.80 MMP2 (0.35) MMP2MMP9MMP8MMP13MMP3
SCHEMBL4447713 0.79 MMP2 (0.41) MMP2MMP9MMP8MMP13MMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8236208-B2 Optical cellulose ester film and manufacturing method thereof, and polarizing plate and liquid crystal display device KONICA MINOLTA OPTO, INC. (JP) 2012-08-07 US disclosed
US-20090081388-A1 Optical Cellulose Ester Film and Manufacturing Method Thereof, and Polarizing Plate and Liquid Crystal Display Device KONICA MINOLTA OPTO, INC. (JP) 2009-03-26 US disclosed