SCHEMBL4449571

SCHEMBL4449571

CCCCC1(c2ccccc2)C(=O)Oc2ccccc21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 4/20 0.48
MMP9 P14780 4/20 0.48
MMP3 P08254 2/20 0.48
CYP2C9 P11712 2/20 0.40
CYP2C19 P33261 2/20 0.40
NPSR1 Q6W5P4 2/20 0.40
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
MMP8 P22894 1/20 0.39
MMP13 P45452 1/20 0.39
RECQL P46063 1/20 0.39
MAPT P10636 1/20 0.38
ELANE P08246 1/20 0.36
CYP1A2 P05177 1/20 0.36
POLB P06746 1/20 0.36
TSHR P16473 1/20 0.36
APEX1 P27695 1/20 0.36
OPRM1 P35372 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3897034 0.94 MMP2 (0.56) MMP2MMP9MMP3CYP2C9CYP2C19
SCHEMBL3896300 0.94 MMP2 (0.56) MMP2MMP9MMP3CYP2C9CYP2C19
SCHEMBL27807661 0.87 BDKRB2 (0.39) MMP2MMP9MMP3CYP2C9CYP2C19
SCHEMBL4445357 0.87 MMP2 (0.42) MMP2MMP9MMP3CYP2C9CYP2C19
SCHEMBL28813338 0.86 MMP2 (0.35) MMP2MMP9MMP3CYP2C9CYP2C19
SCHEMBL1828711 0.86 MMP2 (0.41) MMP2MMP9MMP3CYP2C9CYP2C19
SCHEMBL1557114 0.84 SCN9A (0.35) MMP2MMP9MMP3CYP2C9CYP2C19
SCHEMBL7530635 0.82 MEN1 (0.39) MMP2MMP9MMP3CYP2C9CYP2C19
Amolanone SCHEMBL24472 0.82 SIGMAR1 (0.40) MMP2MMP9MMP3MEN1KMT2A
Amolanone SCHEMBL24473 0.82 SIGMAR1 (0.40) MMP2MMP9MMP3MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006136451-A1 STABILISED POLYPROPYLENE COMPOSITION BOREALIS TECHNOLOGY OY (FI) 2006-12-28 WO claimed
EP-1736506-A1 Stabilised polypropylene composition Borealis Technology Oy (FI) 2006-12-27 EP claimed
CN-104736513-A Hybrid photoinitiators BASF SE 2015-06-24 CN disclosed
US-8236208-B2 Optical cellulose ester film and manufacturing method thereof, and polarizing plate and liquid crystal display device KONICA MINOLTA OPTO, INC. (JP) 2012-08-07 US disclosed
CN-102348761-A Stabilized blends of polyester and polyamide BASF SE 2012-02-08 CN disclosed
CN-102348762-A Stabilized blends of polyesters and polyamides BASF SE 2012-02-08 CN disclosed
US-20090081388-A1 Optical Cellulose Ester Film and Manufacturing Method Thereof, and Polarizing Plate and Liquid Crystal Display Device KONICA MINOLTA OPTO, INC. (JP) 2009-03-26 US disclosed
CN-100412069-C Process for preparation of 3-aryl-benzofuranones CIBA SC HOLDING AG (CH) 2008-08-20 CN disclosed
CN-1890254-A Process for manufacture of pentaerythritol diphosphites DOVER CHEMICAL CORP (US) 2007-01-03 CN disclosed
WO-2006136451-A1 STABILISED POLYPROPYLENE COMPOSITION BOREALIS TECHNOLOGY OY (FI) 2006-12-28 WO disclosed
EP-1736506-A1 Stabilised polypropylene composition Borealis Technology Oy (FI) 2006-12-27 EP disclosed
CN-1235984-C Fluorinated-photoinitiators in dual cure resins CIBA SC HOLDING AG (CH) 2006-01-11 CN disclosed
CN-1214035-C Surface-active photoinitiators CIBA SC HOLDING AG (CH) 2005-08-10 CN disclosed
CN-1474862-A Fluorinated-photoinitiators in dual cure resins �������⻯ѧƷ�ع����޹�˾ 2004-02-11 CN disclosed
CN-1447814-A Surface-active photoinitiators CIBA SC HOLDING AG (CH) 2003-10-08 CN disclosed
CN-1307570-A Process for preparation of 3-aryl-benzofuranones CIBA SC HOLDING AG (CH) 2001-08-08 CN disclosed