SCHEMBL4445503

SCHEMBL4445503

N#Cc1ccc(C2(O)CCCC2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.54
OPRD1 P41143 1/20 0.54
OPRK1 P41145 1/20 0.54
OPRL1 P41146 1/20 0.54
CYP19A1 P11511 2/20 0.45
CCR1 P32246 1/20 0.44
CA12 O43570 1/20 0.43
CA2 P00918 1/20 0.43
CA3 P07451 1/20 0.43
CA6 P23280 1/20 0.43
CA9 Q16790 1/20 0.43
CA14 Q9ULX7 1/20 0.43
DRD2 P14416 1/20 0.41
TRPA1 O75762 1/20 0.41
HRH3 Q9Y5N1 3/20 0.41
MAPKAPK2 P49137 1/20 0.39
MMP3 P08254 1/20 0.39
ENPP2 Q13822 1/20 0.39
ALDH1A1 P00352 1/20 0.38
CYP2A6 P11509 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL249869 0.98 OPRM1 (0.53) OPRM1OPRD1OPRK1OPRL1CYP19A1
SCHEMBL517455 0.96 OPRM1 (0.54) OPRM1OPRD1OPRK1OPRL1CYP19A1
SCHEMBL4821949 0.91 OPRL1 (0.57) OPRM1OPRD1OPRK1OPRL1CYP19A1
SCHEMBL654295 0.84 DRD2 (0.61) OPRM1OPRD1OPRK1OPRL1CYP19A1
SCHEMBL16762049 0.82 OPRL1 (0.50) OPRM1OPRD1OPRK1OPRL1CYP19A1
SCHEMBL249601 0.82 OPRM1 (0.50) OPRM1OPRD1OPRK1OPRL1CYP19A1
SCHEMBL744125 0.81 OPRM1 (0.49) OPRM1OPRD1OPRK1OPRL1CYP19A1
SCHEMBL21077930 0.80 OPRL1 (0.58) OPRM1OPRD1OPRK1OPRL1CYP19A1
SCHEMBL19226358 0.80 OPRM1 (0.58) OPRM1OPRD1OPRK1OPRL1CCR1
SCHEMBL30586005 0.78 ESR1 (0.52) OPRM1OPRD1OPRK1OPRL1CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1937407-B1 SOLUTIONS OF ANHYDROUS LANTHANIDE SALTS AND ITS PREPARATION UNIV MUENCHEN LUDWIG MAXIMILIANS (DE) 2015-04-22 EP disclosed
EP-1937407-B1 SOLUTIONS OF ANHYDROUS LANTHANIDE SALTS AND ITS PREPARATION UNIV MUENCHEN LUDWIG MAXIMILIANS (DE) 2015-04-22 EP disclosed
US-8470982-B2 Solutions of anhydrous lanthanide salts and its preparation LUDWIG-MAXIMILIANS-UNIVERSITAET (DE) 2013-06-25 US disclosed
US-8470982-B2 Solutions of anhydrous lanthanide salts and its preparation LUDWIG-MAXIMILIANS-UNIVERSITAET (DE) 2013-06-25 US disclosed
US-8470982-B2 Solutions of anhydrous lanthanide salts and its preparation LUDWIG-MAXIMILIANS-UNIVERSITAET (DE) 2013-06-25 US disclosed
CN-101277763-B Anhydrous lanthanide salt solutions and their preparation UNIV MUENCHEN L MAXIMILIANS 2012-08-22 CN disclosed
US-20090326235-A1 Solutions of anhydrous lanthanide salts and its preparation LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN (DE) 2009-12-31 US disclosed
US-20090326235-A1 Solutions of anhydrous lanthanide salts and its preparation LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN (DE) 2009-12-31 US disclosed
US-20090326235-A1 Solutions of anhydrous lanthanide salts and its preparation LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN (DE) 2009-12-31 US disclosed
CN-101277763-A Anhydrous lanthanide salt solutions and their preparation UNIV MUENCHEN L MAXIMILIANS (DE) 2008-10-01 CN disclosed
EP-1937407-A1 SOLUTIONS OF ANHYDROUS LANTHANIDE SALTS AND ITS PREPARATION Ludwig-Maximilians-Universität München (DE) 2008-07-02 EP disclosed
WO-2007026014-A1 SOLUTIONS OF ANHYDROUS LANTHANIDE SALTS AND ITS PREPARATION LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN (DE) 2007-03-08 WO disclosed
WO-2007026014-A1 SOLUTIONS OF ANHYDROUS LANTHANIDE SALTS AND ITS PREPARATION LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN (DE) 2007-03-08 WO disclosed
EP-1759765-A1 Solutions of anhydrous lanthanide salts and its preparation Ludwig-Maximilians-Universität München (DE) 2007-03-07 EP disclosed
EP-1759765-A1 Solutions of anhydrous lanthanide salts and its preparation Ludwig-Maximilians-Universität München (DE) 2007-03-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090326235-A1 Solutions of anhydrous lanthanide salts and its preparation SLC39A3, AQP3, IKZF3 OPRM1 2681/4885OPRD1 3538/4885OPRK1 2770/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.