Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30753408 | 0.84 | MAPT (0.42) | MAPTALDH1A1USP2ATML3MBTL1 | |
| SCHEMBL6890425 | 0.82 | LMNA (0.55) | MAPTALDH1A1USP2L3MBTL1TDP1 | |
| SCHEMBL6894569 | 0.82 | CES2 (0.47) | MAPTALDH1A1ATMGAASMN1; SMN2 | |
| SCHEMBL1051575 | 0.81 | TDP1 (0.44) | MAPTALDH1A1USP2ATML3MBTL1 | |
| SCHEMBL6890525 | 0.80 | LMNA (0.61) | MAPTALDH1A1ALOX15HSD17B10GAA | |
| SCHEMBL6895059 | 0.80 | CES2 (0.49) | MEN1KMT2A | |
| SCHEMBL18073 | 0.79 | TDP1 (0.54) | MAPTALDH1A1USP2ATML3MBTL1 | |
| SCHEMBL9353455 | 0.79 | TDP1 (0.54) | MAPTALDH1A1USP2ATML3MBTL1 | |
| SCHEMBL9353461 | 0.79 | TDP1 (0.54) | MAPTALDH1A1USP2ATML3MBTL1 | |
| SCHEMBL9241160 | 0.79 | TDP1 (0.54) | MAPTALDH1A1USP2ATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2189443-B1 | TRICYCLIC AMIDE COMPOUND | RES FOUND ITSUU LAB (JP) | 2013-10-23 | — | — | EP | claimed |
| US-4560751-A | CYCLIZATION OF AMIDO-THIOAMIDE COMPOUND | BASF AKTIENGESELLSCHAFT (DE) | 1985-12-24 | — | — | US | claimed |
| US-4250090-A | COLORFASTNESS; WETFASTNESS; ACID AZO DYES | BASF AKTIENGESELLSCHAFT (DE) | 1981-02-10 | — | — | US | claimed |
| WO-2023210623-A1 | HALOALKYL SULFONE ANILIDE COMPOUND AND HERBICIDE CONTAINING SAME | 株式会社エス・ディー・エス バイオテック | 2023-11-02 | — | — | WO | disclosed |
| EP-2910560-B1 | SILICON-CONTAINING CARBOXYLIC ACID DERIVATIVE | KEMPHYS LTD (JP) | 2017-09-06 | — | — | EP | disclosed |
| US-9353134-B2 | Silicon-containing carboxylic acid derivative | KEMPHYS LTD. (JP) | 2016-05-31 | — | — | US | disclosed |
| EP-2910560-A1 | SILICON-CONTAINING CARBOXYLIC ACID DERIVATIVE | Kemphys Ltd. (JP) | 2015-08-26 | — | — | EP | disclosed |
| US-20150232487-A1 | SILICON-CONTAINING CARBOXYLIC ACID DERIVATIVE | KEMPHYS LTD. (JP) | 2015-08-20 | — | — | US | disclosed |
| US-8895769-B2 | Silicon-containing carboxylic acid derivative | KEMPHYS LTD. (JP) | 2014-11-25 | — | — | US | disclosed |
| US-8895317-B2 | Reagent for measuring active nitrogen | THE UNIVERSITY OF TOKYO (JP) | 2014-11-25 | — | — | US | disclosed |
| US-20140335517-A1 | DETECTION AND TREATMENT OF SCHIZOPHRENIA | RENASCIENCE CO LTD (JP) | 2014-11-13 | — | — | US | disclosed |
| US-4694075-A | DISAZO DYES FOR PAPER | BASF AKTIENGESELLSCHAFT (DE) | 1987-09-15 | — | — | US | disclosed |
| EP-0218206-A2 | Disazo pigments having a piperazine bridging member | BASF Aktiengesellschaft (DE) | 1987-04-15 | — | — | EP | disclosed |
| EP-0189836-A1 | Basic azo dyes | BASF Aktiengesellschaft (DE) | 1986-08-06 | — | — | EP | disclosed |
| EP-0100018-B1 | PROCESS FOR THE PRODUCTION OF 2-N,N-DISUBSTITUTED AMINOTHIAZOLES | BASF Aktiengesellschaft (DE) | 1986-04-02 | — | — | EP | disclosed |
| US-4560751-A | CYCLIZATION OF AMIDO-THIOAMIDE COMPOUND | BASF AKTIENGESELLSCHAFT (DE) | 1985-12-24 | — | — | US | disclosed |
| EP-0100018-A1 | Process for the production of 2-N,N-disubstituted aminothiazoles | BASF Aktiengesellschaft (DE) | 1984-02-08 | — | — | EP | disclosed |
| EP-0035116-A2 | Azo dyestuffs and dyestuff mixtures and their use in dyeing polyesters | BASF Aktiengesellschaft (DE) | 1981-09-09 | — | — | EP | disclosed |
| EP-0034716-A1 | Navy blue dyestuff mixtures and their use in dyeing polyesters | BASF Aktiengesellschaft (DE) | 1981-09-02 | — | — | EP | disclosed |
| US-4250090-A | COLORFASTNESS; WETFASTNESS; ACID AZO DYES | BASF AKTIENGESELLSCHAFT (DE) | 1981-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150232487-A1 | SILICON-CONTAINING CARBOXYLIC ACID DERIVATIVE | CA6, CXCR6, CCR6 | MAPT 4049/4885ALDH1A1 4163/4885USP2 2518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.