Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3593660 | 1.00 | PAX8 (0.35) | PAX8GFERPOLBTNKSMEN1 | |
| SCHEMBL13185877 | 0.89 | GFER (0.36) | GFERPOLBTNKSMEN1KMT2A | |
| SCHEMBL3599584 | 0.83 | MAPK14 (0.37) | PAX8GFERMEN1KMT2A | |
| SCHEMBL3591176 | 0.77 | KCNN4 (0.36) | — | |
| SCHEMBL3592352 | 0.77 | ALDH1A1 (0.36) | GFERMEN1KMT2A | |
| SCHEMBL3593757 | 0.75 | KDM4E (0.39) | POLB | |
| SCHEMBL3589557 | 0.73 | GRM5 (0.40) | GFERPOLBKMT2A | |
| SCHEMBL3585606 | 0.72 | HTR1A (0.38) | GFERPOLBMEN1KMT2A | |
| SCHEMBL14161702 | 0.71 | GFER (0.34) | GFERMEN1KMT2A | |
| SCHEMBL13168227 | 0.71 | LMNA (0.34) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121598-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2009-11-25 | — | — | EP | claimed |
| WO-2008076754-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-06-26 | — | — | WO | claimed |