SCHEMBL4445992

SCHEMBL4445992

C=C(C)C(=O)OCC[Si](OC)(OC)OC.C=C(C)C(=O)OC[SiH2]C(OC)OC

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.37
TSHR P16473 3/20 0.36
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL396764 0.85 TSHR (0.47) THRBTSHRALDH1A1
SCHEMBL183781 0.83 THRB (0.50) THRBTSHRALDH1A1
SCHEMBL4437903 0.81 TSHR (0.33) TSHR
SCHEMBL3206550 0.79 TSHR (0.37) THRBTSHRALDH1A1
SCHEMBL65597 0.76 THRB (0.46) THRBTSHRALDH1A1
SCHEMBL8749908 0.74 THRB (0.58) THRBTSHRALDH1A1
SCHEMBL7637126 0.74 THRB (0.44) THRBTSHRALDH1A1
SCHEMBL7644194 0.74 THRB (0.44) THRBTSHRALDH1A1
SCHEMBL15276 0.74 TSHR (0.55) THRBTSHRALDH1A1
SCHEMBL5446210 0.74 TSHR (0.55) THRBTSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2125833-A1 METHOD FOR THE PRODUCTION OF POLYMERISABLE SILICONES Wacker Chemie AG (DE) 2009-12-02 EP disclosed
WO-2008090012-A1 METHOD FOR THE PRODUCTION OF POLYMERISABLE SILICONES WACKER CHEMIE AG (DE) 2008-07-31 WO disclosed