SCHEMBL4446233

SCHEMBL4446233

C/C(=C\CC(C)OC(N)=O)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.44
CHRM2 P08172 1/20 0.44
CHRM4 P08173 1/20 0.44
CHRM5 P08912 1/20 0.44
CHRM1 P11229 1/20 0.44
CHRM3 P20309 1/20 0.44
CYP2C9 P11712 1/20 0.44
TSHR P16473 1/20 0.44
MAPT P10636 1/20 0.43
GRIK1 P39086 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4446238 1.00 LMNA (0.44) LMNACHRM2CHRM4CHRM5CHRM1
SCHEMBL552061 0.79 TSHR (0.39) TSHR
SCHEMBL1142577 0.79 MGAM (0.38)
SCHEMBL6253819 0.79 CHRNB2 (0.31)
SCHEMBL4933153 0.79 FAAH (0.33)
SCHEMBL6253812 0.79 CHRNB2 (0.31)
SCHEMBL3429210 0.79 APEX1 (0.31) GRIK1
SCHEMBL828377 0.79 APEX1 (0.31) GRIK1
SCHEMBL27220949 0.77 CTSK (0.32)
SCHEMBL8752405 0.77 GRIK1 (0.30) GRIK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1474454-B1 THERMOSETTING COMPOSITIONS CONTAINING ALTERNATING COPOLYMERS OF ISOBUTYLENE TYPE MONOMERS PPG IND OHIO INC (US) 2009-11-18 EP claimed
EP-1474479-B1 POWDER COATING COMPOSITIONS HAVING IMPROVED MAR AND ACID RESISTANCE PPG IND OHIO INC (US) 2008-08-06 EP claimed
WO-2005047234-A1 METHOD FOR PRODUCING CARBAMATE GROUP-CONTAINING (METH)ACRYLIC ESTERS Röhm GmbH & Co. KG (DE) 2005-05-26 WO disclosed