SCHEMBL4446776

SCHEMBL4446776

NC(=O)Oc1ccc(OC(N)=O)c2c(OC(=O)O)ccc(OC(=O)O)c12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
KIF11 P52732 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
CA7 P43166 1/20 0.33
TPMT P51580 1/20 0.33
CA9 Q16790 1/20 0.33
CA14 Q9ULX7 1/20 0.33
TSHR P16473 3/20 0.32
CYP3A4 P08684 2/20 0.32
CYP2C19 P33261 2/20 0.32
POLB P06746 1/20 0.32
PARP1 P09874 1/20 0.32
MAPT P10636 1/20 0.32
RECQL P46063 1/20 0.32
BLM P54132 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3006414 0.90 KDM4E (0.35) KMT2ACA12CA1CA2CA4
SCHEMBL297251 0.81 KDM4E (0.31) TSHRKDM4EALDH1A1GAARAB9A
SCHEMBL7837897 0.76 ALDH1A1 (0.39) MEN1KMT2ACYP2C19POLBMAPT
SCHEMBL7029967 0.72 KMT2A (0.52) MEN1KMT2ACA12CA1CA2
SCHEMBL29728552 0.72 KMT2A (0.52) MEN1KMT2ACA12CA1CA2
SCHEMBL1039198 0.72 MAPK1 (0.36) KMT2ACA12CA1CA2CA4
SCHEMBL9649801 0.71 GAA (0.43) MEN1KMT2ACA12CA1CA2
SCHEMBL17416731 0.70 KEAP1 (0.40) MEN1KMT2ATSHRCYP3A4POLB
SCHEMBL2587831 0.70 KDM4E (0.39) MEN1KMT2APOLBMAPTHSD17B10
SCHEMBL1551337 0.70 GABRP (0.33) TSHRL3MBTL1KDM4EALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7498084-B2 Macromolecular structure, functional device having the same, transistor, and display apparatus using the same SHARP KABUSHIKI KAISHA (JP) 2009-03-03 US disclosed
US-20040201018-A1 Polymer structure and functional element having the same, and transistor and display using the same SHARP KABUSHIKI KAISHA (JP) 2004-10-14 US disclosed