⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7430676 | 0.92 | — | — | |
| SCHEMBL6831867 | 0.90 | — | — | |
| SCHEMBL3900748 | 0.79 | — | — | |
| SCHEMBL15542137 | 0.79 | — | — | |
| SCHEMBL28575500 | 0.74 | — | — | |
| SCHEMBL3025155 | 0.73 | DGAT1 (0.31) | — | |
| SCHEMBL6200371 | 0.72 | ACHE (0.30) | — | |
| SCHEMBL20898651 | 0.72 | — | — | |
| SCHEMBL5787669 | 0.70 | LMNA (0.33) | — | |
| SCHEMBL3708708 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649074-A1 | HIV INTEGRASE INHIBITORS | Bristol-Myers Squibb Company (US) | 2013-10-16 | — | — | EP | claimed |
| WO-2012078844-A1 | HIV INTEGRASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-06-14 | — | — | WO | claimed |
| CN-101925606-A | Compounds comprising a cyclobutoxy group | UCB PHARMA SA | 2010-12-22 | — | — | CN | claimed |
| CN-1759118-B | Diazepinoindole derivatives as kinase inhibitors | PFIZER | 2010-12-08 | — | — | CN | claimed |
| US-7354933-B2 | Protein kinase inhibitors; antitumor agents; such as 5-methyl-1-quinol-4-ylmethyl-3-(4-trifluoromethanesulfonylphenyl)imidazolidine-2,4-dione trifluoroacetate | AVENTIS PHARMA SA (FR) | 2008-04-08 | — | — | US | claimed |
| CN-1759118-A | Diazepinoindole derivatives as kinase inhibitors | PFIZER (US) | 2006-04-12 | — | — | CN | claimed |
| CN-106117312-A | New bonding agent drug conjugate (ADC) and application thereof | 西雅图基因公司 | 2016-11-16 | — | — | CN | disclosed |
| CN-104254342-A | FGRF antibody drug conjugates (ADCs) and the use thereof | SEATTLE GENETICS INC | 2014-12-31 | — | — | CN | disclosed |
| CN-103826661-A | Novel binding agent-drug conjugates (ADCs) and uses thereof | SEATTLE GENETICS INC | 2014-05-28 | — | — | CN | disclosed |
| CN-103764170-A | Novel binder-drug conjugates (ADCs) and their use | SEATTLE GENETICS INC | 2014-04-30 | — | — | CN | disclosed |
| CN-102388039-A | Pyrazole derivatives as CCR4 receptor antagonists | GLAXO GROUP LTD | 2012-03-21 | — | — | CN | disclosed |
| CN-101925606-A | Compounds comprising a cyclobutoxy group | UCB PHARMA SA | 2010-12-22 | — | — | CN | disclosed |
| CN-1759118-B | Diazepinoindole derivatives as kinase inhibitors | PFIZER | 2010-12-08 | — | — | CN | disclosed |
| WO-2008080511-A1 | HETEROARYLCYCLOPROPANECARBOXAMIDES AND THEIR USE AS PHARMACEUTICALS | SANOFI-AVENTIS (FR) | 2008-07-10 | — | — | WO | disclosed |
| CN-100348599-C | Novel fused imidazole derivatives | EISAI CO LTD (JP) | 2007-11-14 | — | — | CN | disclosed |
| CN-1931859-A | New fused imidazole derivative | EISAI CO LTD (JP) | 2007-03-21 | — | — | CN | disclosed |
| CN-1798736-A | Novel quinoline, tetrahydroquinazoline and pyrimidine derivatives and methods of treatment related to their use | ARENA PHARM INC (JP) | 2006-07-05 | — | — | CN | disclosed |
| CN-1759118-A | Diazepinoindole derivatives as kinase inhibitors | PFIZER (US) | 2006-04-12 | — | — | CN | disclosed |
| CN-1678594-A | Morpholin-acetamide derivatives for the treatment of inflammatory diseases | GLAXO GROUP LTD (GB) | 2005-10-05 | — | — | CN | disclosed |
| CN-1675208-A | Novel fused imidazole derivatives | EISAI CO LTD (JP) | 2005-09-28 | — | — | CN | disclosed |