SCHEMBL730349

SCHEMBL730349

CCO[Si](CNC(CC(=O)OC)C(=O)OC)(OCC)OCC

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL730268 0.94 CA12 (0.30) CA12CA1CA2CA9
SCHEMBL728588 0.94 MAPT (0.32) CA12CA1CA2CA9MAPT
SCHEMBL730223 0.85 CA12 (0.33) CA12CA1CA2CA9MGAM
SCHEMBL730300 0.84 L3MBTL1 (0.41) MGAMGAASIMGAM2MAPT
SCHEMBL4447146 0.82 TSHR (0.31)
SCHEMBL4447143 0.82 TSHR (0.31)
SCHEMBL728606 0.81 L3MBTL1 (0.39) MGAMGAASIMGAM2MAPT
SCHEMBL728669 0.80 L3MBTL1 (0.38) MGAMGAASIMGAM2MAPT
SCHEMBL729761 0.78 ALDH1A1 (0.37) MAPT
SCHEMBL730350 0.77 L3MBTL1 (0.34) MGAMGAASIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2393861-B1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-23 EP claimed
US-8138297-B2 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-20 US claimed
US-20100204384-A1 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. 2010-08-12 US claimed
EP-2393861-B1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-23 EP disclosed
US-8138297-B2 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-20 US disclosed
EP-2393861-A1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY Momentive Performance Materials Inc. (US) 2011-12-14 EP disclosed
US-20100204384-A1 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. 2010-08-12 US disclosed
WO-2010091338-A1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2010-08-12 WO disclosed