Azoxystrobin

Azoxystrobin

SCHEMBL4447188

CO/C=C(\C(=O)OC)c1ccccc1Oc1cc(Oc2ccccc2C#N)ncn1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAP4K4 O95819 1/20 0.38
ALDH1A1 P00352 1/20 0.38
HPGD P15428 1/20 0.38
TSHR P16473 1/20 0.38
MAPK14 Q16539 2/20 0.37
SYK P43405 1/20 0.37
SMN1; SMN2 Q16637 3/20 0.37
PIN1 Q13526 1/20 0.37
POLB P06746 1/20 0.36
GAA P10253 1/20 0.36
MAPK1 P28482 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
SCN9A Q15858 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Azoxystrobin SCHEMBL55087 1.00 MAP4K4 (0.38) MAP4K4ALDH1A1HPGDTSHRMAPK14
Azoxystrobin SCHEMBL29362394 1.00 MAP4K4 (0.38) MAP4K4ALDH1A1HPGDTSHRMAPK14
Azoxystrobin SCHEMBL18823 1.00 MAP4K4 (0.38) MAP4K4ALDH1A1HPGDTSHRMAPK14
Azoxystrobin SCHEMBL4113006 1.00 MAP4K4 (0.38) MAP4K4ALDH1A1HPGDTSHRMAPK14
Azoxystrobin SCHEMBL17701154 0.99 MAP4K4 (0.38) MAP4K4ALDH1A1HPGDTSHRMAPK14
Azoxystrobin SCHEMBL17701140 0.97 PIN1 (0.37) MAP4K4ALDH1A1HPGDTSHRMAPK14
Azoxystrobin SCHEMBL6424745 0.94 PIN1 (0.36) MAP4K4ALDH1A1HPGDTSHRMAPK14
Azoxystrobin SCHEMBL17701168 0.93 SYK (0.37) MAP4K4ALDH1A1HPGDTSHRMAPK14
Azoxystrobin SCHEMBL5902501 0.93 PIN1 (0.37) MAP4K4ALDH1A1HPGDTSHRMAPK14
Azoxystrobin SCHEMBL19356835 0.92 PIN1 (0.36) MAP4K4ALDH1A1HPGDTSHRMAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017060917-A1 PROCESS FOR THE PREPARATION OF AZOXYSTROBIN GSP CROP SCIENCE PVT. LTD, (IN) 2017-04-13 WO claimed
US-7622133-B2 Plant protection agents BAYER AKTIENGESELLSCHAFT (DE) 2009-11-24 US claimed
US-20080004299-A1 Plant protection agents MARGOT PAUL 2008-01-03 US claimed
US-20060160833-A1 Plant protection agents MARGOT PAUL 2006-07-20 US claimed
US-20030083340-A1 Plant protection agents MARGOT PAUL (CH) 2003-05-01 US claimed
EP-0944308-B1 Synergistic plant protection agent mixtures BAYER CROPSCIENCE AG (DE) 2003-03-19 EP claimed
EP-0944308-A1 PLANT PROTECTION AGENTS Novartis AG (CH) 1999-09-29 EP claimed
WO-1998025459-A1 PLANT PROTECTION AGENTS NOVARTIS AG (CH) 1998-06-18 WO claimed
US-11214552-B2 Preparation method for azoxystrobin and intermediate thereof PURPANA (BEIJING) TECHNOLOGIES CO., LTD (CN) 2022-01-04 US disclosed
US-20210009532-A1 PREPARATION METHOD FOR AZOXYSTROBIN AND INTERMEDIATE THEREOF PURPANA (BEIJING) TECHNOLOGIES CO., LTD (CN) 2021-01-14 US disclosed
WO-2017060917-A1 PROCESS FOR THE PREPARATION OF AZOXYSTROBIN GSP CROP SCIENCE PVT. LTD, (IN) 2017-04-13 WO disclosed
US-7956009-B2 Fungicidal combinations of active substances BAYER CROPSCIENCE AG (DE) 2011-06-07 US disclosed
US-7956009-B2 Fungicidal combinations of active substances BAYER CROPSCIENCE AG (DE) 2011-06-07 US disclosed
US-20110003011-A1 FUNGICIDAL ACTIVE COMPOUND COMBINATIONS BAYER CROPSCIENCE AG (DE) 2011-01-06 US disclosed
CN-1240332-A plant protection agent NOVARTIS AG (CH) 2000-01-05 CN disclosed
EP-0944308-A1 PLANT PROTECTION AGENTS Novartis AG (CH) 1999-09-29 EP disclosed
EP-0944308-A1 PLANT PROTECTION AGENTS Novartis AG (CH) 1999-09-29 EP disclosed
WO-1998025459-A1 PLANT PROTECTION AGENTS NOVARTIS AG (CH) 1998-06-18 WO disclosed
WO-1998025459-A1 PLANT PROTECTION AGENTS NOVARTIS AG (CH) 1998-06-18 WO disclosed
US-5554619-A Microbicides CIBA-GEIGY CORPORATION (US) 1996-09-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11214552-B2 Preparation method for azoxystrobin and intermediate thereof TET3, HPD, CYP4F11 MAP4K4 2242/4885ALDH1A1 1648/4885HPGD 2863/4885
US-20210009532-A1 PREPARATION METHOD FOR AZOXYSTROBIN AND INTERMEDIATE THEREOF TET3, HPD, CYP4F11 MAP4K4 2242/4885ALDH1A1 1648/4885HPGD 2863/4885
US-20110003011-A1 FUNGICIDAL ACTIVE COMPOUND COMBINATIONS CYP51A1, ERG28, CYP4X1 MAP4K4 3116/4885ALDH1A1 1187/4885HPGD 3299/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.